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Beta secretase (BACE) inhibitors are promising therapeutic compounds currently in clinical phase II/III trials. Preclinical [18F… Expand Our previous study demonstrated the translocation of Aβ1–42 to the nucleus in response to antibiotic treatment, and interpreted… Expand While the peripheral nervous system has the capacity to regenerate following a nerve injury, it is often at a slow rate and… Expand Alzheimer’s disease (AD) is an irreversible, progressive brain disorder that affects about 48 million people worldwide and is the… Expand Environmental pollutants act as risk factors for Alzheimer's disease (AD), mainly affecting the aging population. We investigated… Expand Beta-secretase is the key enzyme involved in Alzheimer's disease thus; inhibition of the enzyme can lead to a potential anti… Expand Alzheimer’s disease (AD) is a complex neurodegenerative disorder with a multi-faceted pathogenesis. So far, the therapeutic… Expand Un compuesto de Formula (I)**Formula** o un tautomero o una forma estereoisomerica del mismo, en la que R1, R2, R3 se seleccionan… Expand The insoluble amyloid deposited extracellularly in the brains of patients with Alzheimer's disease (AD) is composed of amyloid… Expand