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beta-Secretase

Known as: beta secretase 
 
National Institutes of Health

Papers overview

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2018
2018
Our previous study demonstrated the translocation of Aβ1–42 to the nucleus in response to antibiotic treatment, and interpreted… Expand
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2018
2018
Beta secretase (BACE) inhibitors are promising therapeutic compounds currently in clinical phase II/III trials. Preclinical [18F… Expand
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Review
2017
Review
2017
While the peripheral nervous system has the capacity to regenerate following a nerve injury, it is often at a slow rate and… Expand
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Review
2016
Review
2016
Alzheimer’s disease (AD) is an irreversible, progressive brain disorder that affects about 48 million people worldwide and is the… Expand
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Highly Cited
2015
Highly Cited
2015
Environmental pollutants act as risk factors for Alzheimer's disease (AD), mainly affecting the aging population. We investigated… Expand
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2014
2014
Beta-secretase is the key enzyme involved in Alzheimer's disease thus; inhibition of the enzyme can lead to a potential anti… Expand
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Review
2014
Review
2014
Alzheimer’s disease (AD) is a complex neurodegenerative disorder with a multi-faceted pathogenesis. So far, the therapeutic… Expand
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2012
2012
Un compuesto de Formula (I)**Formula** o un tautomero o una forma estereoisomerica del mismo, en la que R1, R2, R3 se seleccionan… Expand
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1996
1996
The insoluble amyloid deposited extracellularly in the brains of patients with Alzheimer's disease (AD) is composed of amyloid… Expand
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