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beta-2 Microglobulin

Known as: Beta-2-Microglobulin, 2-Microglobulin, beta, Beta-2-Microglobulin Protein 
An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule… 
National Institutes of Health

Related topics

Related topics

13 relations
B2M geneBeta-2-microglobulin measurementImmune System ProcessesIn Blood

Papers overview

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Highly Cited
2003
Highly Cited
2003
A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease
The diagnosis of Alzheimer's disease (AD), the most common form of dementia in the general population, usually relies upon the… 
Highly Cited
1999
Highly Cited
1999
Cutting edge: HLA-B27 can form a novel beta 2-microglobulin-free heavy chain homodimer structure.
HLA-B27 has a striking association with inflammatory arthritis. We show that free HLA-B27 heavy chains can form a disulfide… 
Highly Cited
1998
Highly Cited
1998
Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes
This study describes the construction of soluble major histocompatibility complexes consisting of the mouse class I molecule, H… 
Review
1998
Review
1998
The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses
For many viral infections, resolution of illness is associated with long-term host control of viremia rather than viral… 
Highly Cited
1996
Highly Cited
1996
Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP.
Highly Cited
1994
Highly Cited
1994
Involvement of beta 2-microglobulin modified with advanced glycation end products in the pathogenesis of hemodialysis-associated amyloidosis. Induction of human monocyte chemotaxis and macrophage…
beta 2-Microglobulin (beta 2M) is a major constituent of amyloid fibrils in hemodialysis-associated amyloidosis (HAA), a… 
Review
1988
Review
1988
The immunoglobulin superfamily--domains for cell surface recognition.
When Ig chains were first sequenced, segments within the constant regions of H and L chains showed sequence similarities, and… 
Highly Cited
1983
Highly Cited
1983
Striking paucity of HLA-A, B, C and beta 2-microglobulin on human neuroblastoma cell lines.
Monoclonal antibodies to beta 2-microglobulin (beta 2m), and to the native two-chain molecule, were used to assess the expression… 
Highly Cited
1981
Highly Cited
1981
Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin.
We have synthesized two sets of 15-base-long oligodeoxyribonucleotides corresponding to all possible coding sequences for a small… 
Highly Cited
1981
Highly Cited
1981
IMMUNOGENICITY OF HUMAN AMNIOTIC EPITHELIAL CELLS AFTER TRANSPLANTATION INTO VOLUNTEERS
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