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beta-2 Microglobulin

Known as: Beta-2-Microglobulin, 2-Microglobulin, beta, Beta-2-Microglobulin Protein 
An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule… 
National Institutes of Health

Related topics

Related topics

13 relations
B2M geneBeta-2-microglobulin measurementImmune System ProcessesIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Formation of a copper specific binding site in non-native states of beta-2-microglobulin.
A debilitating complication of long-term hemodialysis is the deposition of beta-2-microglobulin (beta2m) as amyloid plaques in… 
Highly Cited
2001
Highly Cited
2001
Transgenic rescue implicates β2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice
Type 1 diabetes in both humans and nonobese diabetic (NOD) mice results from T-cell-mediated autoimmune destruction of insulin… 
Highly Cited
1996
Highly Cited
1996
Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses
A number of investigations have established the critical role of interleukin 4 (IL-4) in mediating the development of T helper… 
Highly Cited
1994
Highly Cited
1994
Self class I molecules protect normal cells from lysis mediated by autologous natural killer cells
The surface expression of given HLA class I alleles protects target cells from lysis mediated by natural killer (NK) clones… 
Highly Cited
1992
Highly Cited
1992
Skin graft rejection by beta 2-microglobulin-deficient mice
Mice homozygous for a beta 2-microglobulin (beta 2-m) gene disruption lack beta 2-m protein and are deficient for functional… 
Highly Cited
1987
Highly Cited
1987
Alterations in the peritoneal transport of water and solutes during peritonitis in continuous ambulatory peritoneal dialysis patients
Abstract. The in situ intraperitoneal volume and the mass transfer area coefficients (MTC) of urea, lactate, creatinine, glucose… 
Highly Cited
1984
Highly Cited
1984
Weak HLA and beta 2-microglobulin expression of neuronal cell lines can be modulated by interferon.
Previous work showed that each of four human neuronal cell lines expresses less than or equal to 0.5% of the HLA-A,B,C and beta 2… 
Highly Cited
1983
Highly Cited
1983
Stable transformation of mouse L cells for human membrane T-cell differentiation antigens, HLA and beta 2-microglobulin: selection by fluorescence-activated cell sorting.
We isolated stable transformants of mouse L cells expressing human cell surface differentiation antigens by using… 
Highly Cited
1982
Highly Cited
1982
Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens.
The complete nucleotide sequence of an HLA-DR antigen-like beta-chain cDNA clone was determined. The 1,080 base pairs include the… 
Highly Cited
1980
Highly Cited
1980
Comparison of methods of evaluating nephrotoxicity of cis‐platinum
The urinary excretion of leucine aminopeptidase (LAP), N‐acetyl‐β‐glucosaminidase (NAG), and β2‐microglobulin was measured in 12… 
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