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beta 2-Glycoprotein I

Known as: beta 2 glycoprotein, EC-VMFa, beta 2-Glycoprotein I [Chemical/Ingredient] 
A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and… 
National Institutes of Health

Related topics

Related topics

15 relations
APOH geneBeta 2 glycoprotein 1 Ab.IgA:ACnc:Pt:Ser:QnBeta 2 glycoprotein 1 Ab.IgG:ACnc:Pt:Ser:QnBeta 2 glycoprotein 1 Ab:PrThr:Pt:Ser:Ord

Broader (1)

Anticoagulants

Narrower (1)

asialo-beta 2-glycoprotein I

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Beta2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome.
The antiphospholipid syndrome is defined by the presence of antiphospholipid antibodies in blood of patients with thrombosis or… 
Review
2008
Review
2008
Oxidation of LDL and its clinical implication.
Highly Cited
2008
Highly Cited
2008
Hydroxychloroquine directly reduces the binding of antiphospholipid antibody-beta2-glycoprotein I complexes to phospholipid bilayers.
Treatment with the antimalarial drug hydroxychloroquine (HCQ) has been associated with reduced risk of thrombosis in the… 
Highly Cited
1997
Highly Cited
1997
Involvement of β2‐glycoprotein I and anticardiolipin antibodies in oxidatively modified low‐density lipoprotein uptake by macrophages
Anticardiolipin antibodies (aCL) in the sera of patients with antiphospholipid syndrome (APS) recognize an altered structure of… 
Highly Cited
1995
Highly Cited
1995
"Anticardiolipin" autoantibodies recognize beta 2-glycoprotein I in the absence of phospholipid. Importance of Ag density and bivalent binding.
"Anticardiolipin" autoantibodies (aCL) bind to anionic phospholipids only in the presence of beta 2-glycoprotein I (beta 2GPI), a… 
Highly Cited
1994
Highly Cited
1994
Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface
Anticardiolipin antibodies (aCL) derived from the sera of individuals exhibiting the antiphospholipid syndrome (APS) directly… 
Highly Cited
1992
Highly Cited
1992
A Phospholipid-β2-Glycoprotein I Complex Is an Antigen for Anticardiolipin Antibodies Occurring in Autoimmune Disease But Not with Infection
Anticardiolipin antibodies (aCL) purified from patients with autoimmune disease have recently been shown to interact with a… 
Highly Cited
1992
Highly Cited
1992
Lupus Anticoagulant Activity Is Frequently Dependent on the Presence of β2-Glycoprotein I
Summary Antiphospholipid antibodies (aPL) are defined by anticardioli-pin antibody (aCL) ELISA and prolongation of phospholipid… 
Highly Cited
1992
Highly Cited
1992
Induction of antiphospholipid autoantibodies by immunization with beta 2 glycoprotein I (apolipoprotein H).
A subset of patients with systemic lupus erythematosus has autoantibodies to acidic phospholipids. Since lipids are poor… 
Highly Cited
1984
Highly Cited
1984
Complete amino acid sequence of human plasma beta 2-glycoprotein I.
We have determined the complete amino acid sequence of beta 2-glycoprotein I (Mr, congruent to 50,000), a human plasma protein… 
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