International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop.
- W. Wilson, A. Gharavi, M. Khamashta
- MedicineArthritis & Rheumatism
- 1 July 1999
Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients.
- R. Cervera, J. Piette, M. Ingelmo
- Medicine, PsychologyArthritis & Rheumatism
- 1 April 2002
An association with SLE, the patient's sex, and the patient’s age at disease onset can modify the disease expression and define specific subsets of APS.
Systemic Vasculitis with Asthma and Eosinophilia: A Clinical Approach to the Churg‐Strauss Syndrome
Drawing on our experience of 16 cases and a review of the English literature, we propose that CSS is under-diagnosed because of exclusive emphasis upon pathologic recognition of the disorder. The…
Systemic Lupus Erythematosus: Clinical and Immunologic Patterns of Disease Expression in a Cohort of 1,000 Patients
- R. Cervera, M. Khamashta, G. Hughes
- Medicine, Biology
- 1 March 1993
The presence of ANA, a high titer of anti-dsDNA, rheumatoid factor, anti-ENA, and antiphospholipid antibodies also distinguished additional homogeneous SLE subsets of clinical significance.
Morbidity and Mortality in Systemic Lupus Erythematosus During a 10-Year Period: A Comparison of Early and Late Manifestations in a Cohort of 1,000 Patients
- R. Cervera, M. Khamashta, G. Hughes
- MedicineMedicine
- 1 September 2003
Most of the SLE inflammatory manifestations appear to be less common after a long-term evolution of the disease, probably reflecting the effect of therapy as well as the progressive remission of the Disease in many patients.
The anticardiolipin syndrome.
- G. Hughes, N. Harris, A. Gharavi
- MedicineJournal of Rheumatology
- 1 October 1985
The “Primary” Antiphospholipid Syndrome: Major Clinical and Serological Features
- R. Asherson, M. Khamashta, G. Hughes
- MedicineMedicine
- 1 November 1989
The group of patients presented appears to be closely related, but distinctly separate from SLE, with a history of deep vein thromboses and a family history of SLE or a familial clotting tendency in a minority.
The management of thrombosis in the antiphospholipid-antibody syndrome.
- M. Khamashta, M. Cuadrado, F. Mujic, N. Taub, B. Hunt, G. Hughes
- MedicineNew England Journal of Medicine
- 13 April 1995
The risk of recurrent thrombosis in patients with the antiphospholipid-antibody syndrome is high and long-term anticoagulation therapy in which the international normalized ratio is maintained at or above 3 is advisable in these patients.
Thrombosis, abortion, cerebral disease, and the lupus anticoagulant.
- G. Hughes
- MedicineBritish medical journal
- 15 October 1983
Few diabetics register on the Disabled Persons Register, but those with disabling complications may find it advantageous to do so and to seek the advice of their local disablement resettlement officer.
Antiphospholipid antibodies
- M. Khamashta, G. Hughes
- MedicineClinical Reviews in Allergy
- 1 September 1994
It is hoped that the results of various controlled therapeutic trials in the APS will indicate better ways of managing these difficult manifestations and the pathogenesis and the optimal management of the syndrome are uncertain.
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