G. Hughes

Publications921
h-index100
Citations44,557
Highly Influential Citations918
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International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop.
Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients.
OBJECTIVE To analyze the clinical and immunologic manifestations of antiphospholipid syndrome (APS) in a large cohort of patients and to define patterns of disease expression. METHODS The clinical… Expand
Systemic Vasculitis with Asthma and Eosinophilia: A Clinical Approach to the Churg‐Strauss Syndrome
Drawing on our experience of 16 cases and a review of the English literature, we propose that CSS is under-diagnosed because of exclusive emphasis upon pathologic recognition of the disorder. The… Expand
Systemic Lupus Erythematosus: Clinical and Immunologic Patterns of Disease Expression in a Cohort of 1,000 Patients
: In the present study we have analyzed the prevalence and characteristics of the most relevant clinical and immunologic features in 1,000 patients with SLE. Several differences in the expression of… Expand
Morbidity and Mortality in Systemic Lupus Erythematosus During a 10-Year Period: A Comparison of Early and Late Manifestations in a Cohort of 1,000 Patients
In the present study, we assessed the frequency and characteristics of the main causes of morbidity and mortality in systemic lupus erythematosus (SLE) during a 10-year period and compared the… Expand
The anticardiolipin syndrome.
The “Primary” Antiphospholipid Syndrome: Major Clinical and Serological Features
The antiphospholipid syndrome--the association of venous and/or arterial thromboses, often accompanied by thrombocytopenia in the presence of the antiphospholipid antibodies ("lupus anticoagulant"… Expand
The management of thrombosis in the antiphospholipid-antibody syndrome.
BACKGROUND The antiphospholipid-antibody syndrome is a thrombophilic disorder in which venous or arterial thrombosis, or both, may occur in patients with antiphospholipid antibodies. The optimal… Expand
Thrombosis, abortion, cerebral disease, and the lupus anticoagulant.
  • G. Hughes
  • Medicine
  • British medical journal
  • 15 October 1983
employment the occupational medical officer should also be notified. Few diabetics register on the Disabled Persons Register, but those with disabling complications may find it advantageous to do so… Expand
Antiphospholipid antibodies
ConclusionConfirmatory evidence that aPL (the LA or aCL) are associated with an increased risk for arterial and venous thrombosis, recurrent spontaneous abortions, and fetal loss has led to increased… Expand
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