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bepotastine

Known as: betotastine, 4-((4-Chlorophenyl)-2-pyridinylmethoxy)-1-piperidinebutanoic Acid, 1-Piperidinebutanoic acid, 4-((4-chlorophenyl)-2-pyridinylmethoxy)- 
National Institutes of Health

Related topics

Related topics

5 relations
Histamine H1 Receptor Antagonists [MoA]bepotastine besilate

Broader (2)

PiperidinesPyridines

Narrower (1)

TAU-284DS

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
A Novel Synthetic Method for Bepotastine, a Histamine H1 Receptor Antagonist
An efficient and alternative synthesis of enantiomerically pure (+)-(S)-4-(4-((4-chlorophenyl)(pyrid-2-yl)methoxy]piperidin-1-yl… 
2013
2013
Efficacy of bepotastine besilate ophthalmic solution 1.5% for seasonal allergic conjunctivitis: a randomized, placebo-controlled, natural exposure, clinical trial.
Allergic conjunctivitis (AC) affects an estimated 20% of the population in the Western world, with a large fraction suffering due… 
2012
2012
Effects of Bepotastine and Fexofenadine on Histamine-Induced Flare, Wheal and Itch
Background: Urticaria is mainly caused by mast cell-derived histamine through the histamine H1 receptor. Antihistamines are… 
Review
2010
Review
2010
Oral Bepotastine
Oral bepotastine is a second-generation histamine H1 receptor antagonist that also suppresses some allergic inflammatory… 
2007
2007
Involvement of histamine released from mast cells in acute radiation dermatitis in mice.
A possible involvement of histamine in acute radiation dermatitis in mice was investigated. The dose of 40 Gy of gamma… 
2007
2007
Oral Administration of Bepotastine Besilate Suppressed Scratching Behavior of Atopic Dermatitis Model NC/Nga Mice
Background: Pruritus is the most severe problem in atopic dermatitis. Even though its mechanism is still not fully understood… 
2005
2005
The effects of olopatadine hydrochloride on the number of scratching induced by repeated application of oxazolone in mice.
2002
2002
The Effect of Prophylactic Treatment with Bepotastine in Patients with Japanese Cedar Pollinosis.
The clinical effect of Bepotastine in patients with Japanese cedar allergy was investigated before and after the start of the… 
1997
1997
[Anti-allergic activity of betotastine besilate (TAU-284), a new anti-allergic drug].
The anti-allergic activity of betotastine besilate (betotastine), a new anti-allergic drug, was investigated in several allergy… 
1997
1997
[Effect of betotastine besilate (TAU-284), a novel anti-allergic agent, on experimental allergic rhinitis].
We investigated the effect of betotastine besilate (betotastine) on the experimental allergic rhinitis. The oral administration… 
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