benzonidazole

Known as: N-benzyl-2-nitro-1-imidazoleacetamide, N-Benzyl-2-nitroimidazole-1-acetamide, 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide 
A nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
05019762018

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND This report describes a real-time PCR (Q-PCR) strategy to quantify Trypanosoma cruzi (T. cruzi) DNA in peripheral… (More)
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Highly Cited
2008
Highly Cited
2008
Nifurtimox and benznidazole are the front-line drugs used to treat Chagas disease, the most important parasitic infection in the… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Benznidazole is effective for treating acute and chronic (recently acquired) Trypanosoma cruzi infection (Chagas… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Benznidazole is effective for treating acute-stage Chagas disease, but its effectiveness for treating indeterminate… (More)
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Highly Cited
2005
Highly Cited
2005
Chagas' disease, caused by Trypanosoma cruzi infection, is one of the main causes of death due to heart failure in Latin American… (More)
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Highly Cited
2002
Highly Cited
2002
The aim of this article is to present an investigation of cure rate, after long follow up, of specific chemotherapy with… (More)
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Highly Cited
1998
Highly Cited
1998
Trypanosoma cruzi populations are subdivided into natural clones that can exhibit considerable genetic differences. It has been… (More)
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Highly Cited
1996
Highly Cited
1996
A new drug screening method was devised utilizing Trypanosoma cruzi cells that express the Escherichia coli beta-galactosidase… (More)
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Highly Cited
1994
Highly Cited
1994
Prescribing etiologic treatment for chronic Chagas' disease is highly controversial because of the difficulties involved in… (More)
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Highly Cited
1987
Highly Cited
1987
The susceptibility and natural resistance to two nitroheterocyclic derivatives used clinically in Chagas disease (nifurtimox and… (More)
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