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benzonidazole
Known as:
N-benzyl-2-nitro-1-imidazoleacetamide
, BENZNIDAZOLE
, N-benzyl-2-nitroimidazole-1-acetamide
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A nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and…
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National Institutes of Health
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Related topics
Related topics
6 relations
Broader (4)
Immunosuppressive Agents
Mutagens
Nitroimidazoles
Trypanocidal Agents
Narrower (1)
Radanil
benznidazole/lomustine
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Inhibitory Receptors Are Expressed by Trypanosoma cruzi-Specific Effector T Cells and in Hearts of Subjects with Chronic Chagas Disease
R. Argüello
,
M. C. Albareda
,
+6 authors
S. Laucella
PLoS ONE
2012
Corpus ID: 3241022
We had formerly demonstrated that subjects chronically infected with Trypanosoma cruzi show impaired T cell responses closely…
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2011
2011
In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against acute and chronic phases of Chagas disease.
M. Sánchez-Moreno
,
A. Sanz
,
+10 authors
M. J. Yunta
Journal of Medicinal Chemistry
2011
Corpus ID: 25021035
The in vivo trypanosomicidal activity of the imidazole-based benzo[g]phthalazine derivatives 1-4 and of the new related pyrazole…
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Highly Cited
2006
Highly Cited
2006
2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents.
M. Boiani
,
L. Boiani
,
+12 authors
Mercedes González
Journal of Medicinal Chemistry
2006
Corpus ID: 9634581
Three series of benzimidazole N-oxide derivatives were developed and were examined for their activity against trypanosomatid…
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Highly Cited
2006
Highly Cited
2006
The Treatment of Chagas Disease (South American Trypanosomiasis)
J. Dias
Annals of Internal Medicine
2006
Corpus ID: 53091550
In every way, Chagas disease remains as a sad shadow that defines poverty, as it reflects the political and social difficulties…
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2001
2001
Cyclic voltammetric studies on nitro radical anion formation from megazol and some related nitroimidazole derivatives
S. Bollo
,
L. Núñez-Vergara
,
M. Bontá
,
G. Chauvière
,
J. Périé
,
J. Squella
2001
Corpus ID: 55351864
2001
2001
Epitope Mapping of trans-Sialidase fromTrypanosoma cruzi Reveals the Presence of Several Cross-Reactive Determinants
T. Pitcovsky
,
J. Mucci
,
+4 authors
O. Campetella
Infection and Immunity
2001
Corpus ID: 5785685
ABSTRACT Trypanosoma cruzi, the agent of Chagas' disease, expresses trans-sialidase, a unique enzyme activity that enables the…
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Review
1999
Review
1999
Parasitological cure of Chagas disease: is it possible? Is it relevant?
Julio A. Urbina
Memórias do Instituto Oswaldo Cruz
1999
Corpus ID: 27757513
Nearly 90 million people (about a quarter ofthe Latin American population) live in zones whereChagas disease is endemic while 18…
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Highly Cited
1999
Highly Cited
1999
QUIMIOTERAPIA DE LA ENFERMEDAD DE CHAGAS
A. Stoppani
1999
Corpus ID: 201949521
1983
1983
Mutagenicity of 2 anti-chagasic drugs and their metabolic deactivation.
R. Nagel
,
I. Nepomnaschy
Mutation research
1983
Corpus ID: 20308908
Highly Cited
1982
Highly Cited
1982
Different behaviors of benznidazole as free radical generator with mammalian and Trypanosoma cruzi microsomal preparations.
S. Moreno
,
R. Docampo
,
R. Mason
,
W. Leon
,
A. Stoppani
Archives of Biochemistry and Biophysics
1982
Corpus ID: 191605
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