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benzimidazolone

Known as: 1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one 
National Institutes of Health

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Benzimidazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Synthesis of 1-isopropyl-3-acyl-5-methyl-benzimidazolone Derivatives and Their Antimicrobial Activity
A series of N-acylated analogues of 1-isopropyl-3-acyl-5-methyl-benzimidazolone were synthesized. Bioassay results indicated that… 
2011
2011
QSAR modeling of the inhibition of reverse transcriptase enzyme with benzimidazolone analogs
The reverse transcriptase inhibitory activity of a set of 27 compounds of benzimidazolone analogs is predicted, applying the… 
2010
2010
Inhibition of trigeminovascular dural nociceptive afferents by Ca2+-activated K+ (MaxiK/BKCa) channel opening
Highly Cited
2003
Highly Cited
2003
CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds.
Activators of the CFTR Cl- channel may be useful for therapy of cystic fibrosis. Short-circuit current (Isc) measurements were… 
2003
2003
Comparative Pharmacology of the Activity of Wild-type and G551D Mutated CFTR Chloride Channel: Effect of the Benzimidazolone Derivative NS004
The pharmacological activation of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel mutated at… 
1994
1994
Gastroprokinetic properties of the benzimidazolone derivative BIMU 1, an agonist at 5-hydroxytryptamine4 and antagonist at 5-hydroxytryptamine3 receptors
We have investigated the in vivo motor stimulating and gastroprokinetic properties of the azabicycloalkyl benzimidazolone… 
1992
1992
5-hydroxytryptamine4 receptor agonists facilitate cholinergic transmission in the circular muscle of guinea pig ileum: antagonism by tropisetron and DAU 6285.
1991
1991
Azabicycloalkyl benzimidazolone derivatives as a novel class of potent agonists at the 5-HT4 receptor positively coupled to adenylate cyclase in braina
SummaryRecent experimental evidence indicates that central 5-HT4 receptors which are positively coupled to adenylate cyclase, are… 
1987
1987
Synthesis and neuroleptic activity of a series of 1-[1-(benzo-1,4-dioxan-2-ylmethyl)-4-piperidinyl]benzim idazolone derivatives.
A series of 1-[1-(benzo-1,4-dioxan-2-ylmethyl)-4-piperidinyl]benzimid azolones with various substituents in both aromatic rings… 
1973
1973
Inhibition of cholinesterase and acetylcholinesterase in vitro by butyrophenone neuroleptics.
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