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benzarone

Known as: 2-ethyl-3-(4'-hydroxybenzoyl)benzofuran, EHBB, benzaron 
National Institutes of Health

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3 relations

Broader (2)

BenzbromaroneFibrinolytic Agents
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Severe hepatotoxicity related to benzarone: a report of three cases with two fatalities.
We report three cases of severe hepatotoxicity related to benzarone, a benzofuran derivative. Our cases include a 35-year-old… 
2004
2004
The effects of antibiotics and uricosuric drugs on the renal elimination of methotrexate and 7-hydroxymethotrexate in rabbits
SummaryIn anesthetized rabbits, continuous infusion of methotrexate (MTX; 30 μg kg-1 min-1) established steadystate plasma… 
1994
1994
Subfulminant hepatitis requiring liver transplantation after benzarone administration.
1991
1991
Liquid chromatography-mass spectrometry in metabolic research. I. Metabolites of benzbromarone in human plasma and urine.
1990
1990
[Hepatitis Caused By Benzarone - a Case-report]
A 46-year-old woman with a previous history of thyroiditis but without clinical evidence of preexisting liver disease presented… 
1988
1988
Benzbromarone disposition and uricosuric action; evidence for hydroxilation instead of debromination to benzarone
SummaryBenzbromarone is one of the main uricosuric drugs currently used. We determined plasma concentrations of benzbromarone… 
1987
1987
Metabolic fate of the thrombolytic agent benzarone in man: comparison with the rat and dog.
1. The metabolic fate of 14C-benzarone in the rat and dog has been compared to that in human subjects. An oral dose was well… 
1984
1984
High-performance liquid chromatographic comparison of in vivo and in vitro drug metabolism.
1982
1982
[The effect of benzarone on serum lipids and arterial wall of cholesterol fed rats].
Rats of BD X strain and SHR/NIH Montreal Ingelheim strain (genetic hypertension) received a diet containing 3.9% cholesterol or 3… 
1972
1972
Metabolism of benzbromarone in man
SummaryBenzbromarone, uniformly labelled with tritium by the Wilzbach procedure, was administered orally to 10 patients. No… 
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