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benfluorex

Known as: Benfluorexum, 1-(3-trifluoromethylphenyl)-2-[N-(2-benzoyloxyethyl)amino]propane, benfluramate 
An antilipidemic agent that decreases the relative rate of hepatic triacylglycerol synthesis. Benfluorex was never approved for use in the United… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
This paper is a personal account on the discovery and characterization of the 5-HT2C receptor (first known as the 5-HT1C receptor… Expand
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2013
2013
The kinetics of drug-receptor interactions can profoundly influence in vivo and in vitro pharmacology. In vitro, the potencies of… Expand
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Highly Cited
2012
Highly Cited
2012
Benfluorex was marketed in France until 2009, despite its similar pharmacological properties with fenfluramine and its… Expand
2012
2012
To estimate the number of deaths from valvular insufficiency caused by the use of the fenfluramine‐derivative benfluorex during… Expand
Highly Cited
2010
Highly Cited
2010
To evaluate and quantify in diabetic patients treated with benfluorex in France, a fenfluramine‐derivated product, a possible… Expand
Highly Cited
2010
Highly Cited
2010
Background Recent case reports suggest that benfluorex, a fenfluramine derivative used in the management of overweight diabetic… Expand
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Highly Cited
2009
Highly Cited
2009
Since 1976, benfluorex has been approved in Europe as a hypolipidemic and hypoglycemic drug, and is commonly used in the… Expand
2006
2006
The authors describe a case of valvular heart disease in a 48‐year‐old woman receiving benfluorex (150 mg t.i.d. for 8 years) and… Expand
Highly Cited
1993
Highly Cited
1993
Insulin resistance, mainly in skeletal muscle, is linked to a cluster of prevalent diseases including NIDDM, dyslipidemias… Expand
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Highly Cited
1975
Highly Cited
1975
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… Expand
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