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bendavia

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A mitochondrial targeting tetrapeptide Bendavia protects lateral line hair cells from gentamicin exposure
The hearing loss induced by aminoglycosides is caused by the permanent loss of mechanosensory hair cells of the inner ear. The… 
2016
2016
BENDAVIA (ELAMIPRETIDE) RESTORES PHOSPHORYLATION OF CARDIAC MYOSIN BINDING PROTEIN C ON SERINE 282 AND IMPROVES LEFT VENTRICULAR DIASTOLIC FUNCTION IN DOGS WITH HEART FAILURE
2014
2014
Abstract 12903: Bendavia (MTP-131), a Mitochondria Targeting Peptide, Normalizes Dysregulation of Mitochondria Fission and Fusion Proteins in Myocardium of Dogs With Chronic Heart Failure
Introduction: Studies of mitochondria (MITO) ultrastructure in heart failure (HF) reveal considerable structural abnormalities… 
2014
2014
A mitochondrial‐targeting peptide (Bendavia) decreases apoptosis and suppresses cardiac fibrosis in the noninfarcted border zone of infarcted hearts (1154.3)
Bendavia is a mitochondrial‐targeting peptide with cardioprotective properties. Apoptosis and cardiac fibrosis contribute to left… 
2013
2013
LONG-TERM THERAPY WITH BENDAVIA (MTP-131), A NOVEL MITOCHONDRIA-TARGETING PEPTIDE, INCREASES MYOCARDIAL ATP SYNTHESIS AND IMPROVES LEFT VENTRICULAR SYSTOLIC FUNCTION IN DOGS WITH CHRONIC HEART…
2013
2013
Long-term therapy with Bendavia (MTP-131), a novel mitochondria-targeting peptide, improves left ventricular systolic function in dogs with chronic heart failure
Background: Mitochondria (MITO) of the failing heart manifest structural and functional abnormalities evidenced by hyperplasia… 
2013
2013
LONG-TERM THERAPY WITH BENDAVIA (MTP-131), A NOVEL MITOCHONDRIA-TARGETING PEPTIDE, REVERSES MITOCHONDRIAL FUNCTIONAL ABNORMALITIES IN LEFT VENTRICULAR MYOCARDIUM OF DOGS WITH ADVANCED HEART FAILURE
2013
2013
Abstract 12105: Chronic Bendavia (a Mitochondrial-Targeting Peptide) Restores Mitochondrial Related Gene Expression in the Noninfarcted Border Zone of Infarcted Hearts
Background: Mitochondrial dysfunction has been implicated in post-infarction heart failure. Bendavia, a mitochondrial-targeting… 
2012
2012
Abstract 10740: Bendavia, a Mitochondria-targeting Peptide, Reduces Reperfusion Injury and Reactive Oxygen Species Levels Through a Mechanism Independent of Direct Oxygen Radical Scavenging: A…
We recently showed that Bendavia, a novel mitochondria-targeting peptide, reduced infarction and no-reflow across several… 
2011
2011
Abstract P169: A Novel Mitochondrial Permeability Transition Pore Inhibitor, Bendavia, Reduces Microvascular Obstruction (No-Reflow) due to Myocardial Ischemia/Reperfusion Injury in the Rabbit
Background: The no-reflow phenomenon is an important detrimental component of reperfusion injury with clinical implications, as… 
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