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bemitradine
Known as:
8-(2-ethoxyethyl)-7-phenyl-1,2,4-triazolo-1,5c-pyrimidine-5-amine
A triazolopyrimidine derivative diuretic. Bemitradine has thiazide-like actions and is a renal vasodilator. Due to its non-genotoxic carcinogenicity…
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Pyrimidines
Triazoles
Narrower (1)
SC 33643
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling.
J. Kramer
,
S. Curtiss
,
+6 authors
R. T. Bunch
Chemical Research in Toxicology
2004
Corpus ID: 13591914
Currently, the only way to identify nongenotoxic hepatocarcinogens is through long-term repeat dose studies such as the 2 year…
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2001
2001
Morphological transformation of Syrian hamster embryo cells at pH 6.7 by bemitradine, a nongenotoxic carcinogen.
Y. Oshiro
,
P. Balwierz
,
D. Morris
,
C. Alden
,
R. T. Bunch
In vitro & Molecular Toxicology
2001
Corpus ID: 21527146
Bemitradine is a compound that was intended for use as a diuretic antihypertensive drug. In the preclinical safety assays, it was…
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1988
1988
Disposition of bemitradine, a renal vasodilator and diuretic, in man.
C. Walls
,
A. Gray
,
+4 authors
J. Steiner
Xenobiotica; the fate of foreign compounds in…
1988
Corpus ID: 24607682
1. 14C-Bemitradine (50 mg) was rapidly and efficiently absorbed (approximately 89%) in man following a single oral dose, as a…
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