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baccatin III
A compound obtained from the needles of the Taxus baccata tree that is used as a precursor of paclitaxel.
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Alkaloids
Taxoids
Microtubule Process
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Microbial transformation of cephalomannine by Luteibacter sp.
Jianhua Li
,
J. Dai
,
Xiaoguang Chen
,
P. Zhu
Journal of Natural Products
2007
Corpus ID: 29292070
Luteibacter sp., a new bacterium isolated from the soil around a Taxus cuspidata Sieb. et Zucc plant, was studied for its…
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2004
2004
Spirobicyclo[2.2.2]octane derivatives: mimetics of baccatin III and paclitaxel (Taxol).
F. Almqvist
,
Sophie Manner
,
Viveca Thornqvist
,
U. Berg
,
M. Wallin
,
T. Frejd
Organic and biomolecular chemistry
2004
Corpus ID: 35459832
The formylated spirobyclic alcohol was computer modeled to be a mimetic of paclitaxel. In this model, the formyl group was used…
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2003
2003
Diastereoselective 14beta-hydroxylation of baccatin III derivatives.
Eleonora Baldelli
,
A. Battaglia
,
+6 authors
D. Pocar
Journal of Organic Chemistry
2003
Corpus ID: 20289746
14beta-Hydroxybaccatin III, a compound with limited availability by natural sources, is the starting material for the synthesis…
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2002
2002
13C NMR investigation of solid-state polymorphism in 10-deacetyl baccatin III.
J. Harper
,
J. Facelli
,
D. H. Barich
,
G. McGeorge
,
A. E. Mulgrew
,
D. Grant
Journal of the American Chemical Society
2002
Corpus ID: 41721468
To investigate the origins of solid-state NMR shift differences in polymorphs, carbon NMR chemical shift tensors are measured for…
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2000
2000
One step more towards taxane production through enhanced Taxus propagation
J. Majada
,
M. Sierra
,
R. Sánchez-Tamés
Plant Cell Reports
2000
Corpus ID: 10762230
Abstract We have developed a high-yielding procedure for the in vitro propagation of juvenile material of Taxus baccata involving…
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Highly Cited
2000
Highly Cited
2000
The configuration of methyl jasmonate affects paclitaxel and baccatin III production in Taxus cells.
Y. Yukimune
,
Y. Hara
,
E. Nomura
,
H. Seto
,
S. Yoshida
Phytochemistry
2000
Corpus ID: 28765144
1994
1994
High-performance liquid chromatography and micellar electrokinetic chromatography of taxol and related taxanes from bark and needle extracts of Taxus species.
K. Chan
,
A. Alvarado
,
M. T. McGuire
,
G. Muschik
,
H. Issaq
,
K. Snader
Journal of chromatography. B, Biomedical…
1994
Corpus ID: 39955660
1994
1994
Site-specific enzymatic hydrolysis of taxanes at C-10 and C-13.
R. Hanson
,
J. Wasylyk
,
V. Nanduri
,
D. Cazzulino
,
R. Patel
,
L. Szarka
Journal of Biological Chemistry
1994
Corpus ID: 13426554
The production of large amounts of paclitaxel for use as an anticancer treatment has been a challenging problem because of the…
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Highly Cited
1993
Highly Cited
1993
A highly efficient route to taxotere by the β-Lactam Synthon Method
I. Ojima
,
Chung‐Ming Sun
,
M. Zucco
,
Young Hoon Park
,
O. Duclos
,
S. Kuduk
1993
Corpus ID: 93155474
1993
1993
Modified taxols, 8. Deacylation and reacylation of baccatin III.
G. Samaranayake
,
K. A. Neidigh
,
David G. I. Kingston
Journal of Natural Products
1993
Corpus ID: 24723511
Hydrogenation of baccatin III over platinum converted it to its hexahydro derivative, and deacylation of this as its 7…
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