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baccatin III

A compound obtained from the needles of the Taxus baccata tree that is used as a precursor of paclitaxel.
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Baccatin III, an intermediate of Taxol biosynthesis and a useful precursor for semisynthesis of the anti-cancer drug, is produced… Expand
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Highly Cited
2006
Highly Cited
2006
Cytochrome P450 monooxygenases play a prominent role in the biosynthesis of the diterpenoid anticancer drug Taxol, as they appear… Expand
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Highly Cited
2002
Highly Cited
2002
A cell suspension culture of Taxus media was established from a stable callus line of this species. The growth rate and… Expand
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Highly Cited
2001
Highly Cited
2001
The ubiquitous Taxol binding site of microtubules also binds newly discovered ligands. We have designed a homogeneous assay for… Expand
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2000
2000
All stereoisomers of methyl jasmonate (MJA) were prepared, and their effects on cell yield and promotion of paclitaxel (Taxol… Expand
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Highly Cited
2000
Highly Cited
2000
The cDNA clone for a 10-deacetylbaccatin III-10-O-acetyl transferase, which catalyzes formation of the last diterpene… Expand
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Highly Cited
1999
Highly Cited
1999
Cell suspension cultures of Taxus canadensis and Taxus cuspidata rapidly produced paclitaxel (Taxol) and other taxoids in… Expand
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Highly Cited
1999
Highly Cited
1999
A new method for the semisynthesis of paclitaxel (Taxol) from baccatin III via a dioxo-oxathiazolidine intermediate is reported. 
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Highly Cited
1996
Highly Cited
1996
Taxus cell culture may be an alternative source of paclitaxel and related taxane production. Significantly increased amounts of… Expand
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Highly Cited
1993
Highly Cited
1993
Taxotere, a highly promising anticancer drug, is synthesized through an efficient coupling of 7,10-diTroc-10-deacetylbaccatin III… Expand
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