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baccatin III

A compound obtained from the needles of the Taxus baccata tree that is used as a precursor of paclitaxel.
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Baccatin III, an intermediate of Taxol biosynthesis and a useful precursor for semisynthesis of the anti-cancer drug, is produced… Expand
Highly Cited
2006
Highly Cited
2006
Cytochrome P450 monooxygenases play a prominent role in the biosynthesis of the diterpenoid anticancer drug Taxol, as they appear… Expand
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Highly Cited
2005
Highly Cited
2005
Paclitaxel and baccatin III-producing cells of Taxus baccata were immobilized within Ca(2+)-alginate beads. Under established… Expand
Highly Cited
2002
Highly Cited
2002
A cell suspension culture of Taxus media was established from a stable callus line of this species. The growth rate and… Expand
Highly Cited
2000
Highly Cited
2000
The cDNA clone for a 10-deacetylbaccatin III-10-O-acetyl transferase, which catalyzes formation of the last diterpene… Expand
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2000
2000
All stereoisomers of methyl jasmonate (MJA) were prepared, and their effects on cell yield and promotion of paclitaxel (Taxol… Expand
Highly Cited
1999
Highly Cited
1999
Cell suspension cultures of Taxus canadensis and Taxus cuspidata rapidly produced paclitaxel (Taxol) and other taxoids in… Expand
Highly Cited
1999
Highly Cited
1999
A new method for the semisynthesis of paclitaxel (Taxol) from baccatin III via a dioxo-oxathiazolidine intermediate is reported. 
Highly Cited
1996
Highly Cited
1996
Taxus cell culture may be an alternative source of paclitaxel and related taxane production. Significantly increased amounts of… Expand
Highly Cited
1993
Highly Cited
1993
Taxotere, a highly promising anticancer drug, is synthesized through an efficient coupling of 7,10-diTroc-10-deacetylbaccatin III… Expand
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