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azaspirane

National Institutes of Health

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SK&F 106615

Broader (1)

Spiro Compounds
antiprimod

Papers overview

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Review
2017
Review
2017
A new approach for treatment of type 1 diabetes: Phytotherapy and phytopharmacology of regulatory T cells
Type 1 diabetes (T1D), which resulting in hyperglycemia, is an autoimmune disease. This disease characterized by destruction of… 
1995
1995
Biochemical and functional analysis of rat bronchoalveolar macrophages containing chemically induced phospholipid inclusions.
Cationic amphiphilic drugs (CADs) are structurally characterized by hydrophobic ring structures and hydrophilic side chains… 
1994
1994
Effects of a novel azaspirane (SK&F 105685) on arthritic lesions in the adjuvant Lewis rat: attenuation of the inflammatory process and preservation of skeletal integrity.
OBJECTIVE To determine the effects of SK&F 105685 (N,N-dimethyl-8,8-dipropyl-2-azaspiro[4.5] decane-2-propanamine dihydrochloride… 
1993
1993
The azaspirane SKF 105685 ameliorates renal allograft rejection in rats.
The azaspirane SKF 105685 (N,N-dimethyl-8, 8-dipropyl-2-azaspiro (4.5) decane-2-propanamine dihydrochloride) has been shown to… 
1993
1993
Effects of SK&F 105685, a novel anti-arthritic agent, on immune function in the dog.
1993
1993
INDUCTION OF NONSPECIFIC X‐IRRADIATION‐RESISTANT SUPPRESSOR CELL ACTIVITY IN VIVO AND PROLONGATION OF VASCULARIZED ALLOGRAFT SURVIVAL BY SK&F 105685, A NOVEL IMMUNOMODULATORY AZASPIRANE
SK&F 105685 is a novel azaspirane with immunosuppressive activity in animal models of autoimmune disease. This study evaluates… 
1993
1993
Prevention of diabetes and induction of non-specific suppressor cell activity in the BB rat by an immunomodulatory azaspirane, SK&F 106610.
Immunomodulatory azaspirane compounds have immunosuppressive activity in animal models of autoimmune disease such as adjuvant… 
1992
1992
Induction of suppressor cell activity in vivo and suppression of lymphoproliferative responses in vitro by SK&F 105.685 in the dog.
1990
1990
Induction of non-specific suppressor cells in normal Lewis rats by a novel azaspirane SK&F 105685.
1983
1983
Phase I study of spirogermanium given daily.
Spirogermanium, an azaspirane compound, has recently had limited clinical trials using a schedule of intravenous injection one to… 
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