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Type 1 diabetes (T1D), which resulting in hyperglycemia, is an autoimmune disease. This disease characterized by destruction of… Expand Azaspiranes are novel macrophage-targeting agents with activity in preclinical animal models of autoimmune disease and… Expand Azaspiranes are cationic amphiphilic compounds that are active in a number of models of autoimmune disease and transplantation… Expand Abstract.Objective and Design: The ability of azaspiranes to modulate the acute inflammatory response in models of skin… Expand The azaspiranes are novel immunomodulators which are effective in a variety of animal models of autoimmune disease and… Expand OBJECTIVE
To evaluate the effect of SK&F 106615 on joint integrity in rats with adjuvant-induced arthritis (AIA).
AIA… Expand The azaspirane SKF 105685 (N,N-dimethyl-8, 8-dipropyl-2-azaspiro (4.5) decane-2-propanamine dihydrochloride) has been shown to… Expand