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azaprophen
Known as:
6-methyl-6-azabicyclo(3.2.1)octan-3-ol 2,2-diphenylpropionate
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Phenylpropionates
Tropanes
Narrower (1)
azaprophen hydrochloride
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Anticonvulsant treatment of nerve agent seizures: anticholinergics versus diazepam in soman-intoxicated guinea pigs
J. McDonough
,
L. Zoeffel
,
J. McMonagle
,
T. Copeland
,
C. Smith
,
T. Shih
Epilepsy Research
1999
Corpus ID: 26047346
Highly Cited
1995
Highly Cited
1995
A study of the N-methyl-D-aspartate antagonistic properties of anticholinergic drugs
J. McDonough
,
T. Shih
Pharmacology, Biochemistry and Behavior
1995
Corpus ID: 23812036
1992
1992
Behavioral effects of some diphenyl-substituted antimuscarinics: Comparison with cocaine and atropine
J. Witkin
,
R. Genovese
,
K. M. Witkin
,
P. Chiang
Pharmacology, Biochemistry and Behavior
1992
Corpus ID: 45819233
1992
1992
Synthesis and muscarinic receptor activity of ester derivatives of 2-substituted 2-azabicyclo[2.2.1]heptan-5-ol and -6-ol.
F. Carroll
,
P. Abraham
,
+4 authors
D. Triggle
Journal of Medicinal Chemistry
1992
Corpus ID: 30485442
Radioligand binding affinities of four new muscarinic antagonists and six potential muscarinic agonists which possess the 2-alkyl…
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Highly Cited
1991
Highly Cited
1991
Anticonvulsant Actions of Anticholinergic Drugs in Soman Poisoning
B. Capacio
,
T. Shih
Epilepsia
1991
Corpus ID: 7058968
Summary: The acute effects of the organophosphorous cholinesterase inhibitor soman include hypersecretions, convulsions, and…
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1991
1991
Physostigmine (alone and together with adjunct) pretreatment against soman, sarin, tabun and VX intoxication.
L. Harris
,
B. Talbot
,
W. J. Lennox
,
D. R. Anderson
,
R. P. Solana
Drug and chemical toxicology (New York, N.Y. )
1991
Corpus ID: 403186
A pretreatment for organophosphorus (OP) anticholinesterase (e.g., soman) intoxication should prevent lethality and convulsions…
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1991
1991
Crystal, solution, and molecular modeling structural properties and muscarinic antagonist activity of azaprophen.
F. Carroll
,
P. Abraham
,
+5 authors
D. Triggle
Journal of Medicinal Chemistry
1991
Corpus ID: 40599939
The structure of azaprophen, which was originally assigned by 1H NMR analysis, was confirmed by X-ray crystallography. A…
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1991
1991
Efficacy Comparison of Two Cholinolytics, Scopolamine and Azaprophen, When Used in Conjunction with Physostigmine and Pyridostigmine for Protection Against Organophosphate Exposure
R. P. Solana
,
C. Gennings
,
+4 authors
L. Harris
1991
Corpus ID: 71352744
Pretreatment with either pyridostigmine (PYR) or physostigmine (PHY) followed by atropineoxime therapy is very effective in…
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1987
1987
6-Methyl-6-azabicyclo[3.2.1]octan-3 alpha-ol 2,2-diphenylpropionate (azaprophen), a highly potent antimuscarinic agent.
F. Carroll
,
P. Abraham
,
+6 authors
P. Chiang
Journal of Medicinal Chemistry
1987
Corpus ID: 19508458
The synthesis and antimuscarinic properties of 6-methyl-6-azabicyclo[3.2.1]octan-3 alpha-ol 2,2-diphenylpropionate (1, azaprophen…
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1987
1987
Comparison of in vitro actions with behavioral effects of antimuscarinic agents.
J. Witkin
,
R. K. Gordon
,
P. Chiang
Journal of Pharmacology and Experimental…
1987
Corpus ID: 6006256
In vitro potencies of a series of muscarinic antagonists were compared with their effects on operant behavior. Ki values for…
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