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avarone

Known as: 2,5-Cyclohexadiene-1,4-dione, 2-((1,2,3,4,4a,7,8,8a-octahydro-1,2,4a,5-tetramethyl-1-naphthalenyl)methyl)-, (1R-(1alpha,2beta,4abeta,8aalpha))- 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

CyclohexenesSesquiterpenes
neoavarone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Further in vitro evaluation of cytotoxicity of the marine natural product derivative 4′-leucine-avarone
The cytotoxicity of 4′-leucine-avarone, amino derivative of the sponge Dysidea avara secondary metabolite avarone, was evaluated… 
2008
2008
Highly efficient total synthesis of the marine natural products (+)-avarone, (+)-avarol, (-)-neoavarone, (-)-neoavarol and (+)-aureol.
Biologically important and structurally unique marine natural products avarone (1), avarol (2), neoavarone (3), neoavarol (4) and… 
2004
2004
Traditional and Modern Biomedical Prospecting: Part II—the Benefits
The progress in molecular and cell biology has enabled a rational exploitation of the natural resources of the secondary… 
Review
2000
Review
2000
Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection
  • E. De Clercq
  • Medicinal research reviews (Print)
  • 2000
  • Corpus ID: 41451102
A large variety of natural products have been described as anti‐HIV agents, and for a portion thereof the target of interaction… 
Highly Cited
1996
Highly Cited
1996
New light on the cell location of avarol within the sponge Dysidea avara (Dendroceratida)
Abstract.Many sponges produce and store secondary metabolites with interesting pharmacological bioactivities. Identification of… 
1996
1996
In vitro effect of avarone and avarol, a quinone/hydroquinone couple of marine origin, on platelet aggregation.
We investigated the effect on human platelet aggregation of the naturally occurring quinone/hydroquinone couple, avarone and… 
Highly Cited
1994
Highly Cited
1994
Avarol and avarone, two new anti-inflammatory agents of marine origin.
Highly Cited
1991
Highly Cited
1991
New avarone and avarol derivatives from the marine sponge Dysidea cinerea.
Six new avarol and avarone derivatives, 3'-hydroxyavarone [3], 3',6'-dihydroxyavarone [4], 6'-hydroxyavarol [5], 6'-acetoxyavarol… 
Highly Cited
1987
Highly Cited
1987
Inhibition of replication of the etiologic agent of acquired immune deficiency syndrome (human T-lymphotropic retrovirus/lymphadenopathy-associated virus) by avarol and avarone.
Avarol and avarone are two antimitotic and antimutagenic agents that preferentially inhibit proliferation of T-cell leukemia… 
Highly Cited
1985
Highly Cited
1985
Potent antileukemic activity of the novel cytostatic agent avarone and its analogues in vitro and in vivo.
Avarone and avarol are novel cytostatic agents which have potent antileukemic activity both in vitro and in vivo (mice). Cell… 
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