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autocrine
Known as:
Autocrine Systems
Organ systems involved in self-stimulation through cellular production of a factor and a specific receptor for it.
National Institutes of Health
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Related topics
Related topics
2 relations
Growth Factor
Broader (1)
Physiology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
R. Nurieva
,
Xuexian O. Yang
,
+8 authors
C. Dong
Nature
2007
Corpus ID: 4431124
After activation, CD4+ helper T (TH) cells differentiate into distinct effector subsets that are characterized by their unique…
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Highly Cited
2003
Highly Cited
2003
BMP‐2 Controls Alkaline Phosphatase Expression and Osteoblast Mineralization by a Wnt Autocrine Loop
G. Rawadi
,
B. Vayssière
,
Fred W. Dunn
,
R. Baron
,
S. Roman-Roman
Journal of Bone and Mineral Research
2003
Corpus ID: 30463698
Wnt/β‐catenin signaling has recently been suggested to be involved in bone biology. The precise role of this cascade in…
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Review
2003
Review
2003
Sphingosine-1-phosphate: an enigmatic signalling lipid
S. Spiegel
,
S. Milstien
Nature reviews. Molecular cell biology
2003
Corpus ID: 22622224
The evolutionarily conserved actions of the sphingolipid metabolite, sphingosine-1-phosphate (S1P), in yeast, plants and mammals…
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Highly Cited
2002
Highly Cited
2002
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
H. Gerber
,
A. K. Malik
,
+6 authors
N. Ferrara
Nature
2002
Corpus ID: 4351698
Vascular endothelial growth factor (VEGF) is a principal regulator of blood vessel formation and haematopoiesis, but the…
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Highly Cited
2001
Highly Cited
2001
Regulatory Activity of Autocrine IL-10 on Dendritic Cell Functions1
S. Corinti
,
C. Albanesi
,
A. la Sala
,
S. Pastore
,
G. Girolomoni
Journal of Immunology
2001
Corpus ID: 675670
IL-10 is a critical cytokine that blocks the maturation of dendritic cells (DCs), but the relevance of autocrine IL-10 on DC…
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Highly Cited
1999
Highly Cited
1999
Hemodynamic shear stress and its role in atherosclerosis.
A. Malek
,
S. Alper
,
S. Izumo
Journal of the American Medical Association (JAMA…
1999
Corpus ID: 22397340
Atherosclerosis, the leading cause of death in the developed world and nearly the leading cause in the developing world, is…
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Highly Cited
1998
Highly Cited
1998
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
V. Fadok
,
D. Bratton
,
A. Konowal
,
Peter W. Freed
,
J. Westcott
,
P. Henson
Journal of Clinical Investigation
1998
Corpus ID: 7707545
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue…
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Highly Cited
1995
Highly Cited
1995
A BDNF autocrine loop in adult sensory neurons prevents cell death
A. Acheson
,
J. Conover
,
+6 authors
R. Lindsay
Nature
1995
Corpus ID: 4316241
DURING the initial phase of their development, sensory neurons of the dorsal root ganglion (DRG) require target-derived trophic…
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Highly Cited
1988
Highly Cited
1988
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
M. Kawano
,
T. Hirano
,
+9 authors
T. Kishimoto
Nature
1988
Corpus ID: 4258236
Human B cell stimulatory factor 2 (BSF-2) was originally charac-terized and isolated as a T cell-derived factor that caused the…
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Review
1985
Review
1985
Autocrine growth factors and cancer
M. Sporn
,
A. Roberts
Nature
1985
Corpus ID: 4336567
The ability of cancer cells to produce and to respond to their own growth factors (autocrine secretion) has become a central…
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