autocrine

Known as: Autocrine Systems 
Organ systems involved in self-stimulation through cellular production of a factor and a specific receptor for it.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Stroma in the tumor microenvironment plays a critical role in cancer progression, but how it promotes metastasis is poorly… (More)
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Highly Cited
2007
Highly Cited
2007
Vascular endothelial growth factor (VEGF) is essential for developmental and pathological angiogenesis. Here we show that in the… (More)
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Highly Cited
2007
Highly Cited
2007
After activation, CD4+ helper T (TH) cells differentiate into distinct effector subsets that are characterized by their unique… (More)
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Highly Cited
2006
Highly Cited
2006
Metastasis is the major cause of cancer morbidity, but strategies for direct interference with invasion processes are lacking… (More)
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Highly Cited
2002
Highly Cited
2002
Vascular endothelial growth factor (VEGF) is a principal regulator of blood vessel formation and haematopoiesis, but the… (More)
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Review
2000
Review
2000
The discovery of leptin in the mid-1990s has focused attention on the role of proteins secreted by adipose tissue. Leptin has… (More)
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Highly Cited
1998
Highly Cited
1998
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue… (More)
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Highly Cited
1988
Highly Cited
1988
Human B cell stimulatory factor 2 (BSF-2) was originally charac-terized and isolated as a T cell-derived factor that caused the… (More)
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Review
1985
Review
1985
The ability of cancer cells to produce and to respond to their own growth factors (autocrine secretion) has become a central… (More)
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Highly Cited
1985
Highly Cited
1985
The autocrine hypothesis proposes that a cell produces and secretes a hormone-like substance that can interact with specific… (More)
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