atorvastatin

Known as: (betaR,deltaR)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid, (betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-pyrrole-1-heptanoic Acid 
A synthetic lipid-lowering agent. Atorvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Tumor necrosis factor α (TNF-α) inhibitors have long been used as disease-modifying agents in immune disorders. Recently… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES This study sought to investigate potential protective effects of atorvastatin in patients with acute coronary… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Atrial fibrillation (AF) after cardiac surgery is associated with increased risk of complications, length of stay, and… (More)
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Highly Cited
2005
Highly Cited
2005
CONTEXT Evidence suggests that more intensive lowering of low-density lipoprotein cholesterol (LDL-C) than is commonly applied… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Type 2 diabetes is associated with a substantially increased risk of cardiovascular disease, but the role of lipid… (More)
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Highly Cited
2003
Highly Cited
2003
The primary objective of this 6-week, parallel-group, open-label, randomized, multicenter trial was to compare rosuvastatin with… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND We observed that the prodrug clopidogrel was less effective in inhibiting platelet aggregation with coadministration… (More)
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Highly Cited
2002
Highly Cited
2002
Statins, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, which are approved for cholesterol reduction, may… (More)
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Highly Cited
2002
Highly Cited
2002
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) may exert direct effects on vascular cells and beneficially… (More)
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Highly Cited
2001
Highly Cited
2001
CONTEXT Patients experience the highest rate of death and recurrent ischemic events during the early period after an acute… (More)
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