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arzoxifene

A synthetic, aromatic derivative with anti-estrogenic properties. Similar to the agent raloxifene, arzoxifene binds to and interacts with estrogen… Expand
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Summary Background Tamoxifen and raloxifene reduce the risk of breast cancer in women at elevated risk of disease, but the… Expand
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Review
2013
Review
2013
Selective estrogen receptor modulators (SERMs) are structurally different compounds that interact with intracellular estrogen… Expand
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Highly Cited
2011
Highly Cited
2011
Arzoxifene is a selective estrogen receptor modulator (SERM) that has been shown to be more potent in preclinical testing than… Expand
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Highly Cited
2007
Highly Cited
2007
PURPOSE To compare the efficacy of arzoxifene with tamoxifen for the treatment of locally advanced or metastatic breast cancer… Expand
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Review
2006
Review
2006
The estrogen receptor alpha (ERalpha) has proven to be the single most important target in breast cancer over the last 30 years… Expand
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2004
2004
Purpose: Arzoxifene, a new selective estrogen receptor modulator with strong breast antiestrogen activity and absence of uterine… Expand
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES The goal of this study was to determine response rate and evaluate toxicity of LY353381 (arzoxifene) in patients with… Expand
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Highly Cited
2002
Highly Cited
2002
The serotonin neural system contributes to cognition and affect, both of which exhibit pathologies with gender bias. We… Expand
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2002
2002
The selective estrogen receptor modulator arzoxifene and the rexinoid LG 100268 were active not only as single agents for… Expand
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Highly Cited
2001
Highly Cited
2001
Arzoxifene ([6-hydroxy-3-[4-[2-(1-piperidinyl)-ethoxy]phenoxy]-2-(4-methoxyphenyl)]benzo[b]thiophene) is a selective estrogen… Expand
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