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arzoxifene
A synthetic, aromatic derivative with anti-estrogenic properties. Similar to the agent raloxifene, arzoxifene binds to and interacts with estrogen…
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National Institutes of Health
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Broader (1)
LY 353381
arzoxifene hydrochloride
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Prevention: Targeted therapy—anastrozole prevents breast cancer
P. Brown
Nature Reviews Clinical Oncology
2014
Corpus ID: 32608358
The recent IBIS-II clinical trial results demonstrate anastrozole reduces breast cancer incidence by 53% in postmenopausal women…
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Review
2013
Review
2013
Breast cancer prevention by antihormones and other drugs: where do we stand?
M. Lazzeroni
,
A. Decensi
Hematology/Oncology Clinics of North America
2013
Corpus ID: 205115747
2012
2012
Breast cancer incidence in postmenopausal women with osteoporosis or low bone mass using arzoxifene
T. J. Powles
,
S. Diem
,
+8 authors
Steven R. Cummings
Breast Cancer Research and Treatment
2012
Corpus ID: 23117278
The Generations trial, a multicenter, placebo-controlled, double-blind trial, compared arzoxifene 20 mg/day and placebo in 9,354…
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2012
2012
Gynecologic effects of arzoxifene in postmenopausal women with osteoporosis or low bone mass
S. Goldstein
,
H. Bhattoa
,
+5 authors
D. Muram
Menopause
2012
Corpus ID: 27588692
ObjectiveThe aim of this study was to report the gynecologic safety findings from the Generations trial, a phase 3 study of the…
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2009
2009
Effects of Arzoxifene on Breast Cancer Incidence in Postmenopausal Women with Osteoporosis or with Low Bone Mass.
T. Powles
,
S. Diem
,
+6 authors
S. Cummings
2009
Corpus ID: 73284833
Precinical and early clinical data indicate that arzoxifene, a third generation SERM, is more potent and bioavailable than…
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Review
2006
Review
2006
Emerging selective estrogen receptor modulators: special focus on effects on coronary heart disease in postmenopausal women.
T. Vogelvang
,
M. J. van der Mooren
,
V. Mijatovic
,
P. Kenemans
Drugs
2006
Corpus ID: 19799761
Menopause, regardless of age at onset, is associated with a marked increase in coronary heart disease (CHD) risk. On the basis of…
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2005
2005
Effect of the Selective Estrogen Receptor Modulator Arzoxifene on Repopulation of Hormone-Responsive Breast Cancer Xenografts between Courses of Chemotherapy
Licun Wu
,
I. Tannock
Clinical Cancer Research
2005
Corpus ID: 7325413
Selective inhibition of repopulation of clonogenic tumor cells between courses of chemotherapy has potential to improve the…
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Review
2004
Review
2004
Use of estrogen antagonists and aromatase inhibitors in breast cancer and hormonally sensitive tumors of the uterine body.
A. Gadducci
,
S. Cosio
,
A. Genazzani
Current opinion in investigational drugs
2004
Corpus ID: 44895581
The new anti-estrogens, including the selective estrogen receptor modulators (e.g., toremifene, droloxifene, idoxifene…
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Review
2003
Review
2003
Novel therapies for osteoporosis
D. Biskobing
Expert Opinion on Investigational Drugs
2003
Corpus ID: 20675062
Osteoporosis remains a significant clinical problem despite effective therapies. Many patients cannot or will not take currently…
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Review
2002
Review
2002
A review of selective estrogen receptor modulators in the treatment of breast and endometrial cancer.
S. Chan
Seminars in Oncology
2002
Corpus ID: 19813833
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