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LY 353381

Known as: LY-353381, LY353381 
National Institutes of Health

Papers overview

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Review
2003
Review
2003
PURPOSE To select a daily dose of arzoxifene (LY353381), a selective estrogen receptor modulator, for use in future studies in… 
Review
2003
Review
2003
BACKGROUND This randomized, double-blind, phase II study assessed two doses of the selective estrogen receptor modulator… 
Highly Cited
2001
Highly Cited
2001
PURPOSE We conducted this phase I trial to determine the safety and toxicity profile of LY353381.HCl-a novel, potent, third… 
Review
2001
Review
2001
  • K. Dhingra
  • Cancer investigation
  • 2001
  • Corpus ID: 12961621
Female hormones, especially estrogens, play an important role in the pathogenesis of breast neoplasms and are a principal… 
Highly Cited
2001
Highly Cited
2001
PURPOSE Cross-resistance is the primary issue facing the evaluation of new antiestrogens to treat metastatic breast cancer… 
Review
2001
Review
2001
  • A. Howell
  • Clinical cancer research : an official journal of…
  • 2001
  • Corpus ID: 11126750
Selective estrogen receptor modulators (SERMs) may act as estrogens or antiestrogens depending on the cell and tissue targets… 
Highly Cited
2000
Highly Cited
2000
Recent data indicate that insulin-like growth factor I (IGF-I) may have a function in mediating the mitogenic effects of 17beta… 
2000
2000
Recent data indicate that insulin-like growth factor I (IGF-I) may have a function in mediating the mitogenic effects of 17beta… 
Review
1999
Review
1999
Selective estrogen receptor modulators (SERMs) are structurally diverse compounds that bind to estrogen receptors (ER) and elicit…