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LY 353381

Known as: LY-353381, LY353381 
 
National Institutes of Health

Papers overview

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2003
2003
OBJECTIVES The goal of this study was to determine response rate and evaluate toxicity of LY353381 (arzoxifene) in patients with… Expand
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2003
2003
Arzoxifene (ARZ) is a selective estrogen receptor (ER) modulator with greater bioavailability than raloxifene which is being… Expand
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2001
2001
PURPOSE We conducted this phase I trial to determine the safety and toxicity profile of LY353381.HCl-a novel, potent, third… Expand
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2001
2001
PURPOSE Cross-resistance is the primary issue facing the evaluation of new antiestrogens to treat metastatic breast cancer… Expand
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Review
2001
Review
2001
Female hormones, especially estrogens, play an important role in the pathogenesis of breast neoplasms and are a principal… Expand
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Review
2001
Review
2001
  • A Howell
  • Clinical cancer research : an official journal of…
  • 2001
  • Corpus ID: 11126750
Selective estrogen receptor modulators (SERMs) may act as estrogens or antiestrogens depending on the cell and tissue targets… Expand
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2000
2000
Recent data indicate that insulin-like growth factor I (IGF-I) may have a function in mediating the mitogenic effects of 17beta… Expand
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2000
2000
Recent data indicate that insulin-like growth factor I (IGF-I) may have a function in mediating the mitogenic effects of 17b… Expand
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Review
1999
Review
1999
Selective estrogen receptor modulators (SERMs) are structurally diverse compounds that bind to estrogen receptors (ER) and elicit… Expand
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1998
1998
LY353381 x HCl is a benzothiophene analog that is structurally related to raloxifene with potent selective estrogen receptor… Expand
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