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arterolane

National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
ABSTRACT The emergence and spread in Southeast Asia of Plasmodium falciparum resistance to artemisinin (ART) derivatives, the… Expand
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2017
2017
Building on insights gained from the discovery of the antimalarial ozonide arterolane (OZ277), we now describe the structure… Expand
2016
2016
AbstractBackgroundChloroquine has been the treatment of choice for acute vivax malaria for more than 60 years. Malaria caused by… Expand
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2015
2015
Antimalarial agents artemisinin and arterolane act via initial reduction of a peroxide bond in a process likely mediated by… Expand
2014
2014
Arterolane (RBx11160, OZ277) maleate is a rapidly acting synthetic trioxolane anti‐malarial. This randomized, placebo controlled… Expand
2011
2011
Artemisinin combination therapies (ACT) represent the current standard of care in the treatment of uncomplicated malaria. The… Expand
2011
2011
Arterolane (RBx 11160) maleate is a novel, rapidly acting synthetic trioxolane antimalarial compound being developed by Ranbaxy… Expand
Highly Cited
2010
Highly Cited
2010
The structure and stereochemistry of the cyclohexane substituents of analogues of arterolane (OZ277) had little effect on potency… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Drug-resistant Plasmodium falciparum malaria necessitates development of novel drugs for treatment.The present study… Expand
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2009
2009
ABSTRACT Peroxidic antimalarials such as the semisynthetic artemisinins are critically important in the treatment of drug… Expand
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