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arpromidine

Known as: (+-)-1-(3-(p-Fluorophenyl)-3-(2-pyridyl)propyl)-3-(3-imidazol-4-ylpropyl)guanidine, Guanidine, N-(3-(4-fluorophenyl)-3-(2-pyridinyl)propyl)-N'-(3-(1H-imidazol-4-yl)propyl)-, N(1)-(3-(4-fluorophenyl)-3-pyridine-2-ylpropyl)-N(2)-(3-(1H-imidazol-4-yl)propyl)guanidine 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

GuanidinesImidazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
NG‐Acylated Aminothiazolylpropylguanidines as Potent and Selective Histamine H2 Receptor Agonists
Bioisosteric replacement of the guanidino group in arpromidine‐like histamine H2 receptor (H2R) agonists by an acylguanidine… 
2006
2006
Arpromidine-related acylguanidines: synthesis and structure-activity relationships of a new class of guanidine-type histamine H2 receptor agonists with reduced basicity
There has been increasing evidence that histamine receptor stimulation might be an interesting aspect for the development of… 
2006
2006
Probing Ligand-Specific Histamine H1- and H2-Receptor Conformations with NG-Acylated Imidazolylpropylguanidines
Impromidine (IMP) and arpromidine (ARP)-derived guanidines are more potent and efficacious guinea pig (gp) histamine H2-receptor… 
Highly Cited
2003
Highly Cited
2003
Multiple Differences in Agonist and Antagonist Pharmacology between Human and Guinea Pig Histamine H1-Receptor
Species isoforms of histamine H2-, H3-, and H4-receptors differ in their pharmacological properties. The study aim was to dissect… 
1998
1998
NPY Y1 antagonists: structure–activity relationships of arginine derivatives and hybrid compounds with arpromidine-like partial structures
1994
1994
Histamine as an autocrine growth factor in experimental mammary carcinomas
In order to determine the role of endogenous histamine in the regulation of cell growth, thein vitro action of fluoromethyl… 
1992
1992
Histamine H1 receptors mediate vasodilation in guinea-pig ileum resistance vessels: characterization with computer-assisted videomicroscopy and new selective agonists.
1991
1991
Therapeutic value of H2-receptor stimulation in congestive heart failure. Hemodynamic effects of BU-E-76, BU-E-75 and arpromidine (BU-E-50) in comparison to impromidine.
Previous studies from our department revealed that congestive heart failure (CHF) is paralleled by a decrease in number of… 
1990
1990
Characterization of histamine H2-receptors in human neutrophils with a series of guanidine analogues of impromidine
SummaryHuman neutrophils possess an NADPH oxidase which catalyzes superoxide (Oinf2sup−) formation and is activated by… 
1990
1990
New perspectives in histamine researchNoordwijkerhout, Netherlands, 68 July 1990
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