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aromatase activity

Catalysis of the reduction of an aliphatic ring to yield an aromatic ring. [GOC:cb]
National Institutes of Health

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2 relations
AromataseCYP19A1 protein, human

Papers overview

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Highly Cited
2006
Highly Cited
2006
HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism.
Cytochrome P450 aromatase (aromatase), a product of the CYP19 gene, catalyzes the synthesis of estrogens from androgens. Given… 
Highly Cited
2005
Highly Cited
2005
Rapid decreases in preoptic aromatase activity and brain monoamine concentrations after engaging in male sexual behavior.
In Japanese quail, as in rats, the expression of male sexual behavior over relatively long time periods (days to weeks) is… 
Highly Cited
2001
Highly Cited
2001
Rapid and reversible inhibition of brain aromatase activity.
Many actions of androgens require their conversion via the enzyme aromatase into oestrogens. Changes in brain aromatase activity… 
Highly Cited
2000
Highly Cited
2000
Profiles of gonadal development, sex steroids, aromatase activity, and gonadotropin II in the controlled sex change of protandrous black porgy, Acanthopagrus schlegeli Bleeker.
The objectives of the present study were to investigate the effects of oral administration of estradiol-17 beta (E(2)) on the sex… 
Highly Cited
1991
Highly Cited
1991
Age-related deficits in brain androgen binding and metabolism, testosterone, and sexual behavior of male rats
Highly Cited
1989
Highly Cited
1989
Intratumoral aromatase as a prognostic factor in human breast carcinoma.
Intratumoral aromatase activity (AA) was measured in 145 samples of human primary breast carcinoma using the tritiated water… 
Highly Cited
1986
Highly Cited
1986
Formation of behaviorally effective 17 beta-estradiol in the dove brain: steroid control of preoptic aromatase.
The preoptic area (POA) of the male dove is a known target area for separable behavioral actions of testosterone and 17 beta… 
Highly Cited
1984
Highly Cited
1984
Regulation of brain aromatase activity in rats.
We studied the distribution and regulation of aromatase activity in the adult rat brain with a sensitive in vitro assay that… 
Highly Cited
1982
Highly Cited
1982
Estrogens augment the stimulation of ovarian aromatase activity by follicle-stimulating hormone in cultured rat granulosa cells.
The effects of estrogens on ovarian aromatase activity were investigated in vitro using granulosa cells from immature… 
Highly Cited
1980
Highly Cited
1980
Alterations in granulosa cell aromatase activity accompanying preovulatory follicular development in the rat ovary with evidence that 5alpha-reduced C19 steroids inhibit the aromatase reaction in…
Locally produced androgens and oestrogens are thought to be important factors in the hormonal regulation of follicular… 
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