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argatroban

Known as: Argipidine, MMTQAP, MPQA 
A synthetic derivative of L-arginine with antithrombotic activity. Argatroban is a univalent and direct inhibitor of fibrin-bound thrombin. This… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (3)

AntithrombinsPipecolic AcidsPlatelet Aggregation Inhibitors
Argatroban:ACnc:Pt:PPP:Qn:ChromoDrug AllergyHemorrhagic DisordersThrombocytopenia

Narrower (3)

MCI 9038MD 805Novastan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Dabigatran, rivaroxaban, apixaban, argatroban and fondaparinux and their effects on coagulation POC and platelet function tests
Abstract Background: In recent years, several selectively acting anticoagulants, including the direct thrombin inhibitors (DTI… 
Review
2010
Review
2010
Agents for the treatment of heparin-induced thrombocytopenia.
Highly Cited
2009
Highly Cited
2009
Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs?
Highly Cited
2005
Highly Cited
2005
Transitioning from Argatroban to Warfarin Therapy in Patients with Heparin-induced Thrombocytopenia
Argatroban, a direct thrombin inhibitor used for thromboprophylaxis or treatment in heparin-induced thrombocytopenia (HIT), is… 
Review
2002
Review
2002
Direct thrombin inhibitors.
Review
2001
Review
2001
Pharmacologic preservation of the hemostatic system during cardiac surgery.
Highly Cited
2001
Highly Cited
2001
FXa-induced responses in vascular wall cells are PAR-mediated and inhibited by ZK-807834.
Highly Cited
2000
Highly Cited
2000
Surface modification of polyethylene balloon catheters for local drug delivery.
Review
1999
Review
1999
Anticoagulation Monitoring during Cardiac Surgery
Anticoagulation Monitoring during Cardiac Surgery: A Review of Current and Emerging Techniques George Despotis;Glenn Gravlee… 
Highly Cited
1992
Highly Cited
1992
TREATMENT OF HEPARIN‐INDUCED THROMBOCYTOPENIA BY USE OF ARGATROBAN, A SYNTHETIC THROMBIN INHIBITOR
ever, despite all efforts, the disease progressed rapidly, the patient’s condition steadily deteriorated and he died in December… 
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