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argatroban

Known as: Argipidine, MMTQAP, MPQA 
A synthetic derivative of L-arginine with antithrombotic activity. Argatroban is a univalent and direct inhibitor of fibrin-bound thrombin. This… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Abstract Background: In recent years, several selectively acting anticoagulants, including the direct thrombin inhibitors (DTI… Expand
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Review
2012
Review
2012
This article describes the pharmacology of approved parenteral anticoagulants. These include the indirect anticoagulants… Expand
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Review
2012
Review
2012
BACKGROUND Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating… Expand
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Highly Cited
2008
Highly Cited
2008
This chapter about the recognition, treatment, and prevention of heparin-induced thrombocytopenia (HIT) is part of the… Expand
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Highly Cited
2008
Highly Cited
2008
This chapter describes the pharmacology of approved parenteral anticoagulants, including the indirect anticoagulants… Expand
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Highly Cited
2007
Highly Cited
2007
The objective of this study was to assess the required dose and anticoagulatory effect of argatroban (Mitsubishi, Pharma… Expand
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Review
2004
Review
2004
This chapter about the recognition, treatment, and prevention of heparin-induced thrombocytopenia (HIT) is part of the Seventh… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Heparin-induced thrombocytopenia (HIT) is an intensely prothrombotic syndrome managed by discontinuation of heparin… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Heparin-induced thrombocytopenia (HIT) is an immune-mediated syndrome caused by heparin. Complications range from… Expand
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Highly Cited
2000
Highly Cited
2000
STUDY OBJECTIVE To determine the pharmacokinetics and pharmacodynamics of argatroban in healthy volunteers and patients with… Expand
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