argatroban

Known as: Argipidine, MMTQAP, MPQA 
A synthetic derivative of L-arginine with antithrombotic activity. Argatroban is a univalent and direct inhibitor of fibrin-bound thrombin. This… (More)

Topic mentions per year

Topic mentions per year

1989-2017
020406019892017

Papers overview

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Review
2016
Review
2016
To review the use of the novel oral anticoagulant (NOAC) agents for the treatment of heparin-induced thrombocytopenia (HIT) from… (More)
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Highly Cited
2008
Highly Cited
2008
This chapter about the recognition, treatment, and prevention of heparin-induced thrombocytopenia (HIT) is part of the… (More)
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2007
2007
BACKGROUND Despite long-term use of argatroban in clinical practice, no dosing recommendations exist for critically ill patients… (More)
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Highly Cited
2005
Highly Cited
2005
We describe a sentence-level opinion detection system. We first define what an opinion means in our research and introduce an… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Heparin-induced thrombocytopenia (HIT) is an intensely prothrombotic syndrome managed by discontinuation of heparin… (More)
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2002
2002
Heparin-induced thrombocytopenia (HIT) is an immune-mediated syndrome associated with thrombosis. Alternative anticoagulation to… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Heparin-induced thrombocytopenia (HIT) is an immune-mediated syndrome caused by heparin. Complications range from… (More)
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Highly Cited
2000
Highly Cited
2000
STUDY OBJECTIVE To determine the pharmacokinetics and pharmacodynamics of argatroban in healthy volunteers and patients with… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The growing use of heparin in acute thrombotic disorders, coupled with the availability of many new antithrombotic… (More)
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1997
1997
Argatroban is a direct antithrombin agent developed for the first time by Okamoto et al in 1978. Unlike heparin, it manifests its… (More)
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