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argatroban

Known as: Argipidine, MMTQAP, MPQA 
A synthetic derivative of L-arginine with antithrombotic activity. Argatroban is a univalent and direct inhibitor of fibrin-bound thrombin. This… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (3)

AntithrombinsPipecolic AcidsPlatelet Aggregation Inhibitors
Argatroban:ACnc:Pt:PPP:Qn:ChromoDrug AllergyHemorrhagic DisordersThrombocytopenia

Narrower (3)

MCI 9038MD 805Novastan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Dabigatran, rivaroxaban, apixaban, argatroban and fondaparinux and their effects on coagulation POC and platelet function tests
Abstract Background: In recent years, several selectively acting anticoagulants, including the direct thrombin inhibitors (DTI… 
Highly Cited
2014
Highly Cited
2014
A Comparison of Lexicon-based Approaches for Sentiment Analysis of Microblog Posts
The exponential growth of available online information provides computer scientists with many new challenges and opportunities. A… 
Highly Cited
2007
Highly Cited
2007
Argatroban Anticoagulation in Critically III Patients
Background: Despite long-term use of argatroban in clinical practice, no dosing recommendations exist for critically ill patients… 
Review
2004
Review
2004
Heparin-induced thrombocytopenia: diagnosis and management.
Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction characterized by thrombocytopenia and a high risk for venous… 
Review
2003
Review
2003
Current anticoagulant therapy--unmet clinical needs.
Highly Cited
2002
Highly Cited
2002
Delayed Argatroban Treatment Reduces Edema in a Rat Model of Intracerebral Hemorrhage
Background and Purpose— Studies indicate that thrombin plays an important role in intracerebral hemorrhage (ICH)–induced edema… 
Highly Cited
2001
Highly Cited
2001
Interpreting the International Normalized Ratio (INR) in Individuals Receiving Argatroban and Warfarin
Summary The effects of argatroban, a direct thrombin inhibitor, on the International Normalized Ratio (INR), activated partial… 
Review
2001
Review
2001
Pharmacologic preservation of the hemostatic system during cardiac surgery.
Highly Cited
1993
Highly Cited
1993
Evidence for a rebound coagulation phenomenon after cessation of a 4-hour infusion of a specific thrombin inhibitor in patients with unstable angina pectoris.
Highly Cited
1992
Highly Cited
1992
Cellular mechanism of thrombin on endothelin-1 biosynthesis and release in bovine endothelial cell.
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