Novastan

Thrombolytic therapy has become a standard treatment for selected patients with acute myocardial infarction (MI). Various… Expand

Unfractionated heparin has enjoyed the sole anticoagulant status for almost half a century. Besides an effective anticoagulant… Expand

OBJECTIVES This study examined the effect of a small-molecule, direct thrombin inhibitor, argatroban, on reperfusion induced by… Expand

A multicenter clinical trial of the thrombin inhibitor argatroban (Novastan; Texas Biotechnology, Houston, TX; Smith-Kline… Expand

Despite the use of potent anticoagulants such as r-hirudin and argatroban, the morbidity/mortality of heparin-induced… Expand

From injury through healing, thrombin has several important functions in blood clotting, subsequent clot lysis, and tissue repair… Expand

Because of the unsatisfactory options available for safe and effective antithrombotic therapy, recent, intense research and… Expand

Heparin-induced thrombocytopenia (HIT) is a syndrome that has been identified with increased frequency. The mortality associated… Expand

We describe a case of a 70-year-old male who underwent coronary artery bypass surgery which was complicated by multiple… Expand

Because of the unsatisfactory options available for safe and effective antithrombotic therapy, recent, intense research and… Expand