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- Publications
- Influence
Efficacy of trimethoprim in murine experimental infection with a thymidine kinase-deficient mutant of Escherichia coli.
- T. Tokunaga, K. Oka, A. Takemoto, Y. Ohtsubo, N. Gotoh, T. Nishino
- Biology, Medicine
- Antimicrobial agents and chemotherapy
- 1 May 1997
The antimicrobial activity of trimethoprim is antagonized by thymidine in in vitro susceptibility tests. The purpose of this investigation was to determine whether this antagonism also occurred… Expand
Light and electron microscopic observations of the lip angiomyoma
- Y. Okada, Y. Kameyama, +4 authors Y. Yamada
- Medicine
- 15 February 1979
Induction of Interferons (IFNs) and Tumor Necrosis Factor (TNF) in Mice by a Novel Glycolipid Trehalose 2,3,6′‐Trimycolate from Rhodococcus aurantiacus (Gordona aurantiaca)
- T. Fujita, N. Sugimoto, +6 authors I. Yano
- Biology, Medicine
- Microbiology and immunology
- 1 June 1990
The immunomodifying activity of a novel mycoloyl glycolipid, trehalose 2,3,6′‐trimycolate (GaGM), from a unique psychrophilic acid‐fast bacterium, Rhodococcus aurantiacus, was examined. ICR mice were… Expand
Simvastatin reduces insulin-like growth factor-1 signaling in differentiating C2C12 mouse myoblast cells in an HMG-CoA reductase inhibition-independent manner.
- T. Ogura, Y. Tanaka, T. Nakata, T. Namikawa, Hirofumi Kataoka, Y. Ohtsubo
- Medicine, Biology
- The Journal of toxicological sciences
- 16 February 2007
Inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase occasionally cause myopathy characterized by weakness, pain, and elevated serum creatine phosphokinase (CK). In this study, we… Expand
Anti-obesity and anti-diabetic activities of a new beta3 adrenergic receptor agonist, (S)-(Z)-[4-[[1-[2-[(2-hydroxy-3-phenoxypropyl)]amino]ethyl]-1-propenyl] phenoxy] acetic acid ethanedioic acid…
- T. Kiso, T. Namikawa, +4 authors Y. Ohtsubo
- Biology, Medicine
- Biological & pharmaceutical bulletin
- 15 October 1999
We investigated the beta-adrenergic receptor (AR) agonistic activities in rats and humans, and the anti-obesity and anti-diabetic activities in KK-Ay mice, of a new beta3-AR agonist, SWR-0342SA… Expand
Structural analyses of a precursory substance of bitterness: new polyisoprenepolyols isolated from an edible mushroom (Hypsizigusmarmoreus) by fast atom bombardment mass spectrometry.
- A. Sawabe, M. Morita, +4 authors T. Okamoto
- Chemistry, Medicine
- Journal of agricultural and food chemistry
- 23 January 1999
New polyisoprenepolyols (hypsiziprenol AA and BA) were isolated from an edible mushroom (Hypsizigus marmoreus). These polyols occur as a mixture of homologous polyisoprene derivatives with 40-70… Expand
Induction of tumoricidal activated macrophages by a liposome-encapsulated glycolipid, trehalose 2,3,6'-trimycolate from Gordona aurantiaca.
- M. Furukawa, Y. Ohtsubo, N. Sugimoto, Y. Katoh, Y. Dohi
- Biology, Medicine
- FEMS microbiology immunology
- 1 September 1990
A mycolic acid-containing glycolipid, trehalose 2,3,6'-trimycolate, prepared from a non-pathogenic acid-fast bacterium Gordona aurantiaca, was shown to induce strong tumoricidal activity in… Expand
cAMP-independent chloride secretion activated by a vasoactive intestinal peptide in a monolayer culture of human bronchial epithelial cells.
- T. Tokunaga, T. Kiso, T. Namikawa, Y. Ohtsubo
- Chemistry, Medicine
- Biological & pharmaceutical bulletin
- 15 July 1999
To investigate the effects of vasoactive intestinal peptide (VIP) on Cl- transport across normal human bronchial epithelial (NHBE) cells grown in a monolayer, changes in short-circuit current (Isc)… Expand
[An immune adjuvant activity of mycolic acid-containing glycolipid, trehalose-2,3,6'-trimycolate, derived from Gordona aurantiaca].
- Y. Ohtsubo, M. Furukawa, +7 authors Y. Dohi
- Biology, Medicine
- Nihon saikingaku zasshi. Japanese journal of…
- 25 March 1989
A mycolic acid-containing glycolipid, trehalose-2,3,6'-trimycolate (GaGM), derived from Gordona aurantiaca, an acid-fast bacterium closely related taxonomically to Mycobacterium, was investigated for… Expand
[In vitro activation of immune cells by a mycolic acid-containing glycolipid, trehalose-2,3,6'-trimycolate, derived from Gordona aurantiaca].
- Y. Ohtsubo, M. Furukawa, +5 authors Y. Dohi
- Chemistry, Medicine
- Nihon saikingaku zasshi. Japanese journal of…
- 25 November 1989
A mycolic acid-containing glycolipid, trehalose-2,3,6'-trimycolate (GaGM), derived from Gordona aurantiaca, an acid-fast bacteria closely related taxonomically to Mycobacterium, was investigated for… Expand