Skip to search formSkip to main contentSkip to account menu

MD 805

Known as: MD-805, MD805 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

argatroban

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Design and synthesis of thrombin inhibitors: analogues of MD-805 with reduced stereogenicity and improved potency.
Mitsubishi's MD-805, a potent and selective inhibitor of thrombin which contains four stereogenic centers, has been the starting… 
1993
1993
Effects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of…
Highly Cited
1991
Highly Cited
1991
Thrombin enhances lung fibroblast proliferation in bleomycin-induced pulmonary fibrosis.
To clarify the role of thrombin in fibroblast growth and the development of pulmonary fibrosis in bleomycin-induced interstitial… 
1991
1991
In Vitro Evaluation of Sustained Drug Release from Biodegradable Elastomer
Poly(DL-lactic acid) (PLA), poly(ε-caprolactone) (PCL), and their copolymers (PLA-CL) with various monomer compositions were… 
1990
1990
The effect of heparin on multiple organ failure and disseminated intravascular coagulation in a sepsis model.
1990
1990
Effect of a synthetic thrombin-inhibitor MD805 on the reaction between thrombin and plasma antithrombin-III.
1989
1989
Choice of anticoagulant in a congenital antithrombin III (AT III)-deficient patient with chronic renal failure undergoing regular haemodialysis.
We describe a 43-year-old male patient with congenital antithrombin III deficiency requiring haemodialysis due to extension of… 
1988
1988
Effect of synthetic thrombin inhibitor (MD805) as an alternative drug on heparin induced thrombocytopenia during hemodialysis.
1987
1987
Plasma antithrombin activity of MD 805 determined by chromogenic substrate during hemodialysis
Anticoagulant activity by a new synthetic substrate (MD805) during the hemodialysis can be assessed with the direct determination… 
1981
1981
Phase One Study of Synthetic Antithrombin Agent (MD-805)
The phase one study was performed by the use of the single and multiple intravenous administration of newly developed synthetic… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)