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arachidonate 8-lipoxygenase

Known as: 8(R)-lipoxygenase, 8-lipoxygenase 
National Institutes of Health

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Arachidonate Lipoxygenases

Papers overview

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2009
2009
Structural basis for pH-dependent alterations of reaction specificity of vertebrate lipoxygenase isoforms.
2004
2004
Upregulation of 8-lipoxygenase in the dermatitis of IkappaB-alpha-deficient mice.
Neonatal mice deficient in IkappaB-alpha, an inhibitor of the ubiquitous transcription factor NF-kappaB, develop severe and… 
2001
2001
A pertussis toxin-sensitive 8-lipoxygenase pathway is activated by a nicotinic acetylcholine receptor in aplysia neurons.
Acetylcholine (ACh) activates two types of chloride conductances in Aplysia neurons that can be distinguished by their kinetics… 
1999
1999
Constitutive expression of 8‐lipoxygenase in papillomas and clastogenic effects of lipoxygenase‐derived arachidonic acid metabolites in keratinocytes
The expression pattern, enzymatic activity, and products of 8‐lipoxygenase (LOX) were analyzed in normal and neoplastic skin of… 
1999
1999
cDNA cloning of 15-lipoxygenase type 2 and 12-lipoxygenases of bovine corneal epithelium.
Highly Cited
1998
Highly Cited
1998
cDNA cloning of a 8-lipoxygenase and a novel epidermis-type lipoxygenase from phorbol ester-treated mouse skin.
1997
1997
Identification of an 8-Lipoxygenase Pathway in Nervous Tissue of Aplysia californica *
Arachidonic acid is converted to (8R)-hydroperoxyeicosa-5,9,11,14-tetraenoic acid (8-HPETE) during incubations with homogenates… 
1991
1991
Investigation of the allene oxide pathway in the coral Plexaura homomalla: formation of novel ketols and isomers of prostaglandin A2 from 15-hydroxyeicosatetraenoic acid.
Highly Cited
1988
Highly Cited
1988
Phorbol ester induction of 8-lipoxygenase in inbred SENCAR (SSIN) but not C57BL/6J mice correlated with hyperplasia, edema, and oxidant generation but not ornithine decarboxylase induction.
Several responses suggested to be critical components of phorbol ester tumor promotion were compared in 12-O-tetradecanoylphorbol… 
Highly Cited
1986
Highly Cited
1986
Discovery of an arachidonic acid C-8 lipoxygenase in the gorgonian coral Pseudoplexaura porosa.
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