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arachidonate 5-lipoxygenase activity

Known as: arachidonic 5-lipoxygenase activity, 5-delta-lipoxygenase activity, 5Delta-lipoxygenase activity 
Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate. [EC:1.13.11.34]
National Institutes of Health

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2 relations
Arachidonate 5-Lipoxygenasearachidonate 12-lipoxygenase activity

Papers overview

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2017
2017
Flower Pollen Extract and its Effect on the Prostate Inhibition of the Arachidonic Acid Metabolism by an Extract from Rye Pollen
Clinical studies with a defined pollen extract preparation document its symptomatic efficacy in patients with benign prostatic… 
2017
2017
United States Patent ( 19 ) Ammon et al . 54 USE OF PREPARATIONS OF CURCUMA PANTS
M. Wichtl (1989) "Teedrogen” second edition, pp. 191-192, 297-298. G. Madaus (1938) 115-1156. Ammon, et al. (1992) Curcumin: a… 
2011
2011
Microenvironment and Immunology Mast Cell 5-Lipoxygenase Activity Promotes Intestinal Polyposis in APC D 468 Mice
Arachidonic acid metabolism has been implicated in colon carcinogenesis, but the role of hematopoietic 5lipoxygenase (5LO… 
2011
2011
Effect of the novel wound healing agent, OPAL A on leukotriene B 4 production in human neutrophils and 5-lipoxygenase activity RussellFD,WindeggerT,HamiltonKD&CheethamNWH
OPAL A is a papaya pulp that is heated and alkalised with bicarbonate (the OPAL process) and is undergoing clinical trials for… 
1998
1998
Evaluation of the cutaneous anti-inflammatory activity of azaspiranes
Abstract.Objective and Design: The ability of azaspiranes to modulate the acute inflammatory response in models of skin… 
1998
1998
Substituted condensed heterocyclic compound, method of pharmacological effect, method of inhibition of 5-lipoxygenase activity, inhibition of lipid peroxides production or blood sugar level decrease
FIELD: chemistry of heterocyclic compounds, biochemistry. SUBSTANCE: invention relates to novel heterocyclic compounds of the… 
1989
1989
[Inhibitory effect of amlexanox (AA-673) on the immunological and non-immunological release of histamine or leukotrienes].
The effect of amlexanox on the non-immunological or immunological release of histamine or leukotrienes (LTs) from passively… 
1987
1987
[Effect of SIN-1 on the synthesis of leukotrienes in human polymorphonuclear cells].
Leukotriene (LT) synthesis triggered with ionophore A23187 or inflammatory stimuli (PAF, fMLP) in human polymorphonuclear… 
1984
1984
U-60,257 has no effect on the metabolism of arachidonic acid in nonstimulated human polymorphonuclear leukocytes.
When human polymorphonuclear leukocytes (PMNL) were incubated with exogenous 14C-arachidonic acid only traces of 5-lipoxygenase… 
1982
1982
Predominant synthesis of 5-hydroxyeicosatetraenoic acid by a cloned mastocytoma P-815 line, 2-E-6 cells.
Since mouse mast tumor P-815 cells produce the slow reacting substance of anaphylaxis, their 5-lipoxygenase activity was examined…