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arachidonate 5-lipoxygenase activity

Known as: arachidonic 5-lipoxygenase activity, 5-delta-lipoxygenase activity, 5Delta-lipoxygenase activity 
Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate. [EC:1.13.11.34]
National Institutes of Health

Related topics

Related topics

2 relations
Arachidonate 5-Lipoxygenasearachidonate 12-lipoxygenase activity

Papers overview

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2005
2005
Attenuation of breast tumor cell growth by conjugated linoleic acid via inhibition of 5-lipoxygenase activating protein.
1998
1998
Evaluation of the cutaneous anti-inflammatory activity of azaspiranes
Abstract.Objective and Design: The ability of azaspiranes to modulate the acute inflammatory response in models of skin… 
1991
1991
Differential actions of diacyl- and alkylacylglycerols in priming phospholipase A2, 5-lipoxygenase and acetyltransferase activation in human neutrophils.
Highly Cited
1989
Highly Cited
1989
Involvement of glutathione peroxidase activity in the stimulation of 5-lipoxygenase activity by glutathione-depleting agents in human polymorphonuclear leukocytes.
We recently demonstrated activation of 5-lipoxygenase activity in human polymorphonuclear leukocytes (PMN) on preincubation of… 
1989
1989
Stimulation of 5-lipoxygenase activity under conditions which promote lipid peroxidation.
The characteristics of hydroperoxide activation of 5-lipoxygenase were examined in the high speed supernatant fraction prepared… 
1989
1989
Cerebral edema induced by arachidonic acid: role of leukocytes and 5-lipoxygenase products.
Arachidonic acid is released from cellular phospholipid membranes after brain injury associated with vasogenic edema… 
1988
1988
Activation of the Arachidonate 5‐Lipoxygenase Pathway in the Canine Basilar Artery After Experimental Subarachnoidal Hemorrhage
Abstract: Severe cerebral vasospasm as confirmed by an‐giography was induced in dogs by injection of autologous blood into the… 
1986
1986
5-lipoxygenase from rat PMN lysate.
1986
1986
Modulation of the 5-lipoxygenase activity of MC-9 mast cells: activation by hydroperoxides.
1985
1985
Increased activity of 5-lipoxygenase in polymorphonuclear leukocytes from asthmatic patients.
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