apomine

Known as: TETRAISOPROPYL 2-(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)ETHYL-1,1-BIPHOSPHONATE, Tetraisopropyl-2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethylidene-1,1-diphosphonate, tetraisopropyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-ethyl-1,1-bisphosphonate 
A 1,1-bisphosphonate ester with potential antineoplastic and hypocholesterolemic activities. SR-45023A binds to hydroxyapatite crystals in the bone… (More)
National Institutes of Health

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Topic mentions per year

1970-2018
02419702018

Papers overview

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2012
2012
BACKGROUND Osteosarcoma is the most frequent malignant primary bone tumor that occurs mainly in the young, with an incidence peak… (More)
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2010
2010
In this work optical properties of titanium dioxide nanoparticles were studied. Titanium dioxide nanoparticles were synthesized… (More)
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2009
2009
Apomine is a novel compound that inhibits the mevalonate/isoprenoid pathway of cholesterol synthesis and may prove effective as a… (More)
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2008
2008
In mice, cocaine is detoxified to inactive products by butyrylcholinesterase (BChE) and carboxylesterase. In human beings… (More)
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2007
2007
To validate cholinesterase activity as a biomarker of pesticide exposure, we characterized the tissue distribution (whole body… (More)
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2005
2005
The 1,1-bisphosphonate ester family member apomine (SR-45023A) is known to have anti-tumour activity in various cancer cell types… (More)
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2004
2004
AIMS 1) To characterize the population pharmacokinetics of apomine in healthy males and in male and female patients with solid… (More)
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2000
2000
Apomine (SR-45023A) is a new antineoplastic compound which is currently in clinical trials and representative of the family of… (More)
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1994
1994
During chicken neurogenesis, the sequential expression of butyrylcholinesterase (BChE) and acetylcholinesterase (AChE) between… (More)
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1984
1984
  • J. G. Clement
  • Fundamental and applied toxicology : official…
  • 1984
Various doses of CBDP (2-(2- methylphenoxy )-4H-1,3,2- benzodioxaphosphorin -2-oxide), a metabolite of tri-o-cresyl phosphate… (More)
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