apocrine metaplasia

A morphologic finding indicating the alteration of the glandular acinar epithelial cells to apocrine sweat gland cells.
National Institutes of Health

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Adenocarcinoma with Apocrine MetaplasiaBreast Ductal AdenomaBreast Sclerosing Adenosis

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Apocrine Metaplasia of Breast

Papers overview

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2009
2009
Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort.
Invasive apocrine carcinomas (IACs), as defined by morphological features, correspond to 0.3-4% of all invasive ductal carcinomas… (More)
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2007
2007
Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia.
The identification as well as the molecular characterization of breast precancerous lesions in terms of increased risk of… (More)
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2002
2002
Expression of c-erbB2, p53, Bcl-2, Bax, c-myc and Ki-67 in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast
Molecular evidence has recently suggested a number of different pathways leading to the development of ductal carcinoma of the… (More)
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Highly Cited
2002
Highly Cited
2002
Pathobiology of preoperative chemotherapy: findings from the National Surgical Adjuvant Breast and Bowel (NSABP) protocol B-18.
BACKGROUND Examination was performed on pathologic material from patients enrolled in the National Surgical Adjuvant Breast… (More)
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2002
2002
C-myc oncoprotein expression and gene amplification in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast.
Overexpression and/or amplification of c-myc oncogene are known to occur in human breast carcinomas, particularly those of high… (More)
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Highly Cited
2001
Highly Cited
2001
High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss.
We performed high-resolution allelotyping for loss of heterozygosity (LOH) analysis on microdissected samples from 45 primary… (More)
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1997
1997
Immunohistochemical analysis of apocrine breast lesions. Consistent over-expression of androgen receptor accompanied by the loss of estrogen and progesterone receptors in apocrine metaplasia and…
Apocrine phenotype is observed in a spectrum of breast epithelial lesions spanning from benign metaplasias to apocrine carcinoma… (More)
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1991
1991
Atypical apocrine metaplasia in sclerosing lesions of the breast: a study of 51 patients.
Sclerosing breast lesions with cytologically atypical apocrine metaplasia present a difficult diagnostic problem. The clinical… (More)
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1987
1987
Apocrine cystic metaplasia: subgross pathology and prevalence in cancer-associated versus random autopsy breasts.
Focal apocrine metaplasia was studied in 293 whole human breasts by a subgross sampling technique with histologic confirmation… (More)
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1987
1987
Mammary cancer antigen recognized by monoclonal antibody B72.3 in apocrine metaplasia of the human breast.
Monoclonal antibody B72.3 recognizing a pan-associated carcinoma antigen expressed also in metastatic human breast cancer cells… (More)
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