Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

apicularen A

Known as: apicularen 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Background: Apicularen is a specific V-ATPase inhibitor that binds to the VO complex of the holoenzyme. Results: Apicularen binds… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Review
2009
Review
2009
Acidity is one of the main features of the tumors. The V-ATPase is the primary responsible for the control of tumor… Expand
2006
2006
[Structure: see text] A de novo approach to the formal total synthesis of the macrolide natural product (-)-apicularen A has been… Expand
Highly Cited
2005
Highly Cited
2005
BackgroundV-ATPases constitute a ubiquitous family of heteromultimeric, proton translocating proteins. According to their… Expand
  • table 1
  • table 2
Highly Cited
2004
Highly Cited
2004
  • Qibin Su, J. Panek
  • Journal of the American Chemical Society
  • 2004
  • Corpus ID: 28506465
Complete details of an asymmetric synthesis of apicularen (1) are described. The synthesis has been accomplished using a highly… Expand
2003
2003
Apicularen A (1) and related benzolactone acylenamines belong to a growing class of novel natural products possessing highly… Expand
  • figure 1
  • figure 2
  • table 1
2003
2003
A synthesis of apicularen precursor (-)-6 in 18 steps from D-glucal is reported. As (+)-6 has been converted into the potent… Expand
2003
2003
In RAW 264.7 cells, a mouse leukaemic monocyte cell line, apicularen A decreased cell growth and survival as assessed by 3‐(4,5… Expand
2002
2002
[reaction: see text] An approach to the macrocyclic core of apicularen A is described. Thus, cross-coupling of the aryl triflate… Expand
Highly Cited
2000
Highly Cited
2000
Abstract The potent cytostatic agent apicularen A belongs to a growing class of macrocyclic salicylates with unique biological… Expand
  • figure 2