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apicularen A

Known as: apicularen 
National Institutes of Health

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1 relation

Broader (1)

Bridged Bicyclo Compounds, Heterocyclic

Papers overview

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2014
2014
PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells
Combination therapy is key to improving cancer treatment efficacy. Phorbol 12-myristate 13-acetate (PMA), a well-known PKC… 
Review
2012
Review
2012
Synthesis of myxobacteria metabolites
Myxobacteria are an excellent source of novel secondary metabolites with a range of biological activities. This review details… 
Review
2011
Review
2011
Vacuolar H(+)-ATPases: intra- and intermolecular interactions.
2007
2007
Apicularen A Induces Cell Death through Fas Ligand Up-Regulation and Microtubule Disruption by Tubulin Down-Regulation in HM7 Human Colon Cancer Cells
Purpose: Apicularen A has been shown to cause growth inhibition and apoptosis in several cancer cell lines. However, the… 
2007
2007
Side-chain truncation of apicularen A by olefin cross-metathesis with ethylene.
The three olefinic double bonds of natural apicularen A (1a) were cleaved by olefin cross-metathesis in the presence of ethylene… 
2006
2006
De novo formal synthesis of (-)-apicularen A via an iterative asymmetric hydration sequence.
[Structure: see text] A de novo approach to the formal total synthesis of the macrolide natural product (-)-apicularen A has been… 
2006
2006
Nitric Oxide Production by the Vacuolar-Type ( H )-ATPase Inhibitors Bafilomycin A 1 and Concanamycin A and Its Possible Role in Apoptosis in RAW 264 . 7 Cells
In the mouse leukemic monocyte cell line RAW 264.7, the vacuolar-type (H )-ATPase (V-ATPase) inhibitors bafilomycin A1 and… 
2005
2005
Induction of apoptosis by apicularen A in human promyelocytic leukemia cell line HL-60.
Apicularen A, a macrolide isolated from the myxobacterial genus Chondromyces, suppressed the proliferation of human promyelocytic… 
2005
2005
Induction of Nitric Oxide Production by the Cytostatic Macrolide Apicularen A [2,4-Heptadienamide, N-[(1E)-3-[(3S,5R,7R,9S)-3,4,5,6,7,8,9,10-octahydro-7,14 Dihydroxy-1-oxo-5,9-epoxy-1H-2…
We previously reported that apicularen A [2,4-heptadienamide, N-[(1E)-3-[(3S,5R,7R,9S)-3,4,5,6,7,8,9,10-octahydro-7,14 dihydroxy… 
2003
2003
Induction of apoptosis of RAW 264.7 cells by the cytostatic macrolide apicularen A
In RAW 264.7 cells, a mouse leukaemic monocyte cell line, apicularen A decreased cell growth and survival as assessed by 3‐(4,5… 
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