Skip to search formSkip to main contentSkip to account menu

aphidicolin glycinate

Known as: AphiG, aphidicolin-17-glycinate 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Aphidicolin
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Индекс ВИЗГ – новый мультипараметрический показатель для рака предстательной железы
Serum of 336 patients with primary prostate cancer (PC) with baseline total prostate-specific antigen level (totPSA) < 30.0 ng/ml… 
2005
2005
Increased systemic efficacy of aphidicolin encapsulated in liposomes.
Aphidicolin, a tetracyclic diterpene antibiotic produced by Cephalosporium aphidicola, is under investigation as anti-cancer drug… 
2004
2004
Activity of aphidicolin glycinate alone or in combination with cisplatin in a murine ovarian tumor resistant to cisplatin
SummaryAphidicolin, a reversible inhibitor of DNA polymerase α and δ, has recently been reported to reverse the resistance to… 
1999
1999
Aphidicolin glycinate inhibits human neuroblastoma cell growth in vivo.
Aphidicolin is a fungal derived tetracyclic diterpene antibiotic. It is selectively toxic for neuroblastoma (NB) cells in vitro… 
1995
1995
CRC/EORTC/NCI Joint Formulation Working Party: experiences in the formulation of investigational cytotoxic drugs.
The pharmaceutical formulation of a new anti-tumour agent has often been perceived as the bottleneck in anti-cancer drug… 
Highly Cited
1994
Highly Cited
1994
Antitumor activity and biochemical effects of aphidicolin glycinate (NSC 303812) alone and in combination with cisplatin in vivo.
Aphidicolin, an inhibitor of DNA polymerases alpha and delta, is cytotoxic in vitro against tumor cells. The poor solubility of… 
Highly Cited
1991
Highly Cited
1991
Phase I and clinical pharmacological evaluation of aphidicolin glycinate.
The toxicity profile and the pharmacokinetics of aphidicolin glycinate, a water-soluble analogue of aphidicolin, have been… 
1991
1991
Lack of significant modulation of the formation and removal of platinum-DNA adducts by aphidicolin glycinate in two logarithmically-growing ovarian tumour cell lines in vitro.
Two recently established human ovarian carcinoma cell lines (JA-T and TR175) have been used to study the effects of aphidicolin… 
1990
1990
The effect of DNA polymerase inhibitors on the cytotoxicity of cisplatin in human ovarian carcinoma cells.
We examined the effect of specific inhibitors of DNA polymerases alpha and delta, and beta, on cisplatin (DDP) cytotoxicity in… 
1989
1989
A gas chromatographic mass spectrometric assay for the determination of aphidicolin in plasma of cancer patients.
A gas chromatographic-mass spectrometric (GC-MS) method is described for the determination of the novel anticancer agent… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)