anthrapyrazole

Known as: oxanthrazole 
An antineoplastic antibiotic that intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2016
024619852016

Papers overview

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2007
2007
The DNA binding properties of three cation-substituted anthrapyrazole derivatives of emodin with calf thymus DNA were… (More)
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1991
1991
Thirty-one patients with advanced breast cancer were treated with CI941, an anthrapyrazole structurally related to mitoxantrone… (More)
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1990
1990
Piroxantrone (PRX, NSC 349174) is one of the first of a new class of intercalating agents, the anthrapyrazoles, to undergo… (More)
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1989
1989
Oxantrazole (now designated as piroxantrone) is an anthrapyrazole analog under evaluation as a potentially useful anthracycline… (More)
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1988
1988
The binding constants for interaction of several novel anthra[1,9-cd]pyrazol-6(2H)-ones (anthrapyrazoles) with DNA have been… (More)
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1987
1987
Chromophore modification of the anthracenediones related to mitoxantrone in an attempt to provide agents with diminished or no… (More)
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1987
1987
The anthrapyrazole CI941 is one of a new series of DNA complexing drugs which displays high level broad spectrum antitumour… (More)
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1986
1986
The effects of three anthrapyrazoles and an aminoacridine derivative on doxorubicin- and iron-stimulated lipid peroxidation in… (More)
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1986
1986
A series of anthrapyrazoles was examined for their cytotoxic effect on P388 cells resistant (P388R) to anthracyclines, N-[4-(9… (More)
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1985
1985
A series of 5-[(aminoalkyl)amino]-substituted anthra[1,9-cd] pyrazol-6(2H)ones (anthrapyrazoles) were synthesized. These… (More)
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