anterograde axonal transport

Known as: anterograde axon cargo transport 
The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons. [ISBN… (More)
National Institutes of Health

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Cytoplasm of axon

Papers overview

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Highly Cited
2011
Highly Cited
2011
Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
Binding of target-derived neurotrophins to Trk receptors at nerve terminals is required to stimulate neuronal survival… (More)
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Highly Cited
2008
Highly Cited
2008
Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia.
Frontotemporal dementia (FTD) is characterized by cognitive and behavioral changes and, in a significant subset of patients… (More)
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Highly Cited
2004
Highly Cited
2004
Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport.
In several neurodegenerative diseases, axonal degeneration occurs before neuronal death and contributes significantly to patients… (More)
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Highly Cited
2001
Highly Cited
2001
Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP
Proteolytic processing of amyloid precursor protein (APP) generates amyloid-β peptide and has been implicated in the pathogenesis… (More)
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Review
2001
Review
2001
Anterograde axonal transport, transcytosis, and recycling of neurotrophic factors
Traditional views of neurotrophic factor biology held that trophic factors are released from target cells, retrogradely… (More)
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Review
1998
Review
1998
Neurotrophin trafficking by anterograde transport
The ever-unfolding biology of NGF is consistent with a target-derived retrograde mode of action in peripheral and central neurons… (More)
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Highly Cited
1997
Highly Cited
1997
Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport.
A sensitive immunohistochemical technique was used, along with highly specific affinity-purified antibodies to brain-derived… (More)
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Highly Cited
1996
Highly Cited
1996
Anterograde axonal tracing with the subunit B of cholera toxin: a highly sensitive immunohistochemical protocol for revealing fine axonal morphology in adult and neonatal brains
We report an improved immunohistochemical protocol for revealing anterograde axonal transport of the subunit B of cholera toxin… (More)
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Highly Cited
1995
Highly Cited
1995
The neuron-specific kinesin superfamily protein KIF1A is a uniqye monomeric motor for anterograde axonal transport of synaptic vesicle precursors
Axonal transport has been intensively examined as a good model for studying the mechanism of organelle transport in cells, but it… (More)
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Highly Cited
1990
Highly Cited
1990
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.
In the brains of aged humans and cases of Alzheimer disease, deposits of amyloid in senile plaques are located in proximity to… (More)
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