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androgen biosynthetic process

Known as: androgen synthesis, androgen formation, androgen anabolism 
The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1953-2018
0204019532017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer.
PURPOSE Persistence of ligand-mediated androgen receptor signaling has been documented in castration-resistant prostate cancers… (More)
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2010
2010
Aggressive interactions rapidly increase androgen synthesis in the brain during the non-breeding season.
In male song sparrows (Melospiza melodia), territorial challenges during the breeding season can rapidly increase circulating… (More)
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Highly Cited
2004
Highly Cited
2004
Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study.
BACKGROUND Congenital adrenal hyperplasia with apparent combined P450C17 and P450C21 deficiency is associated with accumulation… (More)
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2003
2003
Estrogen receptor-alpha gene deficiency enhances androgen biosynthesis in the mouse Leydig cell.
Leydig cells, which produce the primary male steroid hormone testosterone (T), express the two estrogen receptor (ER) subtypes… (More)
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Highly Cited
2000
Highly Cited
2000
Improvement in mood and fatigue after dehydroepiandrosterone replacement in Addison's disease in a randomized, double blind trial.
Dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) are adrenal precursors of steroid biosynthesis and centrally acting… (More)
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1999
1999
Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry.
An important source of androgens in the human prostate are those synthesized locally from the inactive adrenal precursor… (More)
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1998
1998
Hormonal effects of flutamide in young women with polycystic ovary syndrome.
Anovulation in women with polycystic ovary syndrome (PCOS) is the direct effect of high local androgen concentrations on the… (More)
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1996
1996
The zona reticularis is the site of biosynthesis of dehydroepiandrosterone and dehydroepiandrosterone sulfate in the adult human adrenal cortex resulting from its low expression of 3 beta…
Based on indirect evidence, it has often been assumed that the zona reticularis of the adult human adrenal cortex is the source… (More)
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Highly Cited
1994
Highly Cited
1994
Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries.
The aim of this study was to examine the hypothesis that hypersecretion of ovarian androgens in polycystic ovary syndrome results… (More)
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1987
1987
Heterodimers and homodimers of inhibin subunits have different paracrine action in the modulation of luteinizing hormone-stimulated androgen biosynthesis.
Inhibin, a gonadal hormone capable of preferential suppression of pituitary follicle-stimulating hormone (FSH) secretion, has… (More)
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