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anaphase-promoting complex location

Known as: anaphase promoting complex, APC, anaphase promoting complex location 
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The anaphase promoting complex/cyclosome (APC/C) E3 ligase controls mitosis and nonmitotic pathways through interactions with… Expand
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Highly Cited
2009
Highly Cited
2009
Oncogenic mutations in the small GTPase Ras are highly prevalent in cancer, but an understanding of the vulnerabilities of these… Expand
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Review
2008
Review
2008
The maintenance and preservation of distinct phases during the cell cycle is a highly complex and coordinated process. It is… Expand
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Review
2006
Review
2006
  • J. Peters
  • Nature Reviews Molecular Cell Biology
  • 2006
  • Corpus ID: 31962403
The anaphase promoting complex/cyclosome (APC/C) is a ubiquitin ligase that has essential functions in and outside the eukaryotic… Expand
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Review
2006
Review
2006
A driving force of the cell cycle is the activation of cyclin-dependent kinases (CDKs), the activities of which are controlled by… Expand
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Review
2005
Review
2005
Abnormal chromosome content — also known as aneuploidy — is the most common characteristic of human solid tumours. It has… Expand
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Highly Cited
2001
Highly Cited
2001
The mitotic checkpoint prevents cells with unaligned chromosomes from prematurely exiting mitosis by inhibiting the anaphase… Expand
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Highly Cited
1998
Highly Cited
1998
The tetratricopeptide repeat (TPR) is a degenerate 34 amino acid sequence identified in a wide variety of proteins, present in… Expand
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Highly Cited
1998
Highly Cited
1998
Proteolysis of mitotic cyclins depends on a multisubunit ubiquitin-protein ligase, the anaphase promoting complex (APC… Expand
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Highly Cited
1995
Highly Cited
1995
The ubiquitin-mediated degradation of mitotic cyclins is required for cells to exit from mitosis. Previous work with cell-free… Expand
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