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anaphase-promoting complex location

Known as: anaphase promoting complex, APC, anaphase promoting complex location 
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit… 
National Institutes of Health

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anaphase-promoting complex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Aurora-A kinase interacting protein 1 (AURKAIP1) promotes Aurora-A degradation through an alternative ubiquitin-independent pathway.
Mitotic Aurora-A is an oncogene, which undergoes a cell-cycle-dependent regulation of both its synthesis and degradation… 
Highly Cited
2006
Highly Cited
2006
Roles of the anaphase-promoting complex/cyclosome and of its activator Cdc20 in functional substrate binding
The anaphase-promoting complex/cyclosome (APC/C) is a multisubunit ubiquitin-protein ligase that targets for degradation cell… 
Highly Cited
2006
Highly Cited
2006
Non-cell-autonomous rescue of anaphase-promoting complex function revealed by mosaic analysis of HOBBIT, an Arabidopsis CDC27 homolog
The Arabidopsis HOBBIT (HBT) gene encodes a homolog of the CDC27 anaphase-promoting complex/cyclosome subunit and is essential… 
Highly Cited
2006
Highly Cited
2006
Human PIF Helicase is Cell Cycle Regulated and Associates with Telomerase
The evolutionarily conserved PIF1 DNA helicase family is important for the maintenance of genome stability in the yeast… 
Highly Cited
2005
Highly Cited
2005
The Drosophila Bub3 protein is required for the mitotic checkpoint and for normal accumulation of cyclins during G2 and early stages of mitosis
During mitosis, a checkpoint mechanism delays metaphase-anaphase transition in the presence of unattached and/or unaligned… 
2004
2004
Transcriptional Abnormality of the hsMAD2 Mitotic Checkpoint Gene Is a Potential Link to Hepatocellular Carcinogenesis
MAD2 is localized to kinetochores of unaligned chromosomes, where it inactivates the anaphase-promoting complex/cyclosome, thus… 
Highly Cited
2003
Highly Cited
2003
Developmental defects observed in hypomorphic anaphase-promoting complex mutants are linked to cell cycle abnormalities
In C. elegans, mutants in the anaphase-promoting complex or cyclosome (APC/C) exhibit defects in germline proliferation, the… 
Review
1999
Review
1999
Progression into and out of mitosis.
1999
1999
The Schizosaccharomyces pombe dim1+ Gene Interacts with the Anaphase-Promoting Complex or Cyclosome (APC/C) Component lid1+ and Is Required for APC/C Function
ABSTRACT The Schizosaccharomyces pombe dim1 + gene is required for entry into mitosis and for chromosome segregation during… 
Highly Cited
1997
Highly Cited
1997
The Serine/Threonine Phosphatase PP5 Interacts with CDC16 and CDC27, Two Tetratricopeptide Repeat-containing Subunits of the Anaphase-promoting Complex*
The evolutionarily conserved multisubunit complex known as the cyclosome or anaphase-promoting complex is involved in catalyzing… 
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