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anaphase-promoting complex
Known as:
Anaphase Promoting Complex
, Anaphase-Promoting Complex-Cyclosome
, Anaphase-Promoting Complex-Cyclosome [Chemical/Ingredient]
An E3 ubiquitin ligase primarily involved in regulation of the metaphase-to-anaphase transition during MITOSIS through ubiquitination of specific…
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National Institutes of Health
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Related topics
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8 relations
In Blood
Process of secretion
anaphase-promoting complex location
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Erratum: The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites
Kyungsoo Ha
,
Chengxia Ma
,
+13 authors
Pumin Zhang
Nature communications
2017
Corpus ID: 33296878
[This corrects the article DOI: 10.1038/ncomms15751.].
2012
2012
Proteasome-Dependent Disruption of the E3 Ubiquitin Ligase Anaphase-Promoting Complex by HCMV Protein pUL21a
Anthony R. Fehr
,
Nathaniel C. Gualberto
,
John P Savaryn
,
S. Terhune
,
Dong Yu
PLoS pathogens
2012
Corpus ID: 14134433
The anaphase-promoting complex (APC) is an E3 ubiquitin ligase which controls ubiquitination and degradation of multiple cell…
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Highly Cited
2012
Highly Cited
2012
Filamin A Regulates Neural Progenitor Proliferation and Cortical Size through Wee1-Dependent Cdk1 Phosphorylation
Gewei Lian
,
Jie Lu
,
+4 authors
V. Sheen
The Journal of Neuroscience
2012
Corpus ID: 14279884
Cytoskeleton-associated proteins play key roles not only in regulating cell morphology and migration but also in proliferation…
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2012
2012
Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells
V. Yu
,
C. Marion
,
Theresa Austria
,
J. Yeh
,
A. Schönthal
,
L. Dubeau
International journal of cancer
2012
Corpus ID: 222786
Cancers that develop in BRCA1 mutation carriers are usually near tetraploid/polyploid. This led us to hypothesize that BRCA1…
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2010
2010
Substrate degradation by the anaphase promoting complex occurs during mitotic slippage.
Jinho Lee
,
J. A. Kim
,
R. Margolis
,
R. Fotedar
Cell cycle
2010
Corpus ID: 37545613
Microtubule targeting drugs are successful in chemotherapy because they indefinitely activate the spindle assembly checkpoint…
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Review
2010
Review
2010
Tension Management in the Kinetochore
K. Bloom
,
E. Yeh
Current Biology
2010
Corpus ID: 9576521
2010
2010
Requirements and Reasons for Effective Inhibition of the Anaphase Promoting Complex Activator Cdh1
J. Robbins
,
F. Cross
Molecular biology of the cell
2010
Corpus ID: 25440596
Inhibitory phosphorylation of Cdh1 by CDK and Polo kinase has been proposed to inactivate APC-Cdh1. Through an exact gene…
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Review
2010
Review
2010
ReviewTension Management in the Kinetochore
K. Bloom
,
E. Yeh
2010
Corpus ID: 36981857
The kinetochore is the protein machine built at the centromere that integrates mechanical force and chemical energy from dynamic…
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2007
2007
Regulation of Gene Expression in Bovine Blastocysts in Response to Oxygen and the Iron Chelator Desferrioxamine1
A. Harvey
,
K. Kind
,
J. G. Thompson
Biology of reproduction
2007
Corpus ID: 9524481
Abstract Low (2%) oxygen conditions during postcompaction culture of bovine blastocysts improve embryo quality and are associated…
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Highly Cited
2004
Highly Cited
2004
Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1.
David V. Hansen
,
A. Loktev
,
Kenneth H. Ban
,
P. Jackson
Molecular biology of the cell
2004
Corpus ID: 39122444
Progression through mitosis requires activation of cyclin B/Cdk1 and its downstream targets, including Polo-like kinase and the…
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