anabaseine
National Institutes of Health
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BACKGROUND & AIMS
The nervous system, through the vagus nerve, controls inflammation by decreasing the release of tumor necrosis…
Nemertines are a phylum of carnivorous marine worms that possess a variety of alkaloidal, peptidic or proteinaceous toxins that…
The discovery of the acetylcholine binding proteins (AChBPs) has provided critical soluble surrogates for examining structure and…
The nicotinic receptor drug candidate, 3-(2,4-dimethoxybenzylidene)-anabaseine (also known as GTS-21; DMXBA), its hydroxy…
The goals of this study were to develop compounds that were selective and highly efficacious agonists at alpha-7 receptors, while…
Naturally occurring toxins can often serve as useful chemical tools for investigating signalling processes in nervous and other…