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amyloid precursor protein metabolic process

Known as: APP metabolic process, APP metabolism, amyloid precursor protein metabolism 
The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Azure B affects amyloid precursor protein metabolism in PS70 cells.
Review
2012
Review
2012
Influence of apolipoprotein E and its receptors on cerebral amyloid precursor protein metabolism following traumatic brain injury.
Traumatic brain injury (TBI) is the leading cause of mortality and disability among young individuals in our society, and… 
2009
2009
Changes in the mechanisms of brain adaption during postnatal ontogeny of rats exposed to prenatal hypoxia
We have previously shown that acute hypoxia during embryogenesis impaired learning and memory processes during rat ontogeny [1… 
2008
2008
The cholesterol transport inhibitor U18666a regulates amyloid precursor protein metabolism and trafficking in N2aAPP "Swedish" cells.
Cholesterol transport is a key regulator of amyloid precursor protein (APP) processing and beta-amyloid (Abeta production… 
2007
2007
Statins differentially affect amyloid precursor protein metabolism in presymptomatic PS1 and non-PS1 subjects.
T he putative potential of statins to retard the onset and progression of Alzheimer disease (AD) remains controversial. Statin… 
2007
2007
Apolipoprotein E genotype and alpha-tocopherol modulate amyloid precursor protein metabolism and cell cycle regulation.
Apolipoprotein E4 (apoE4) genotype is associated with an increased risk for Alzheimer's disease (AD). This is thought to be in… 
2003
2003
Characterization of the effect of ganstigmine (CHF2819) on amyloid precursor protein metabolism in SH-SY5Y neuroblastoma cells
Summary. We have investigated the effect of ganstigmine (CHF2819), a novel geneserine derived acetylcholinesterase (AChE… 
Review
1998
Review
1998
Cellular and molecular basis of beta-amyloid precursor protein metabolism.
In molecular neurobiology, perhaps no molecule has been as thoroughly examined as Alzheimer's beta-amyloid precursor protein… 
Review
1997
Review
1997
Mother's legacy: mitochondrial DNA mutations and Alzheimer's disease.
Review
1996
Review
1996
Neurotransmitters, signal transduction and second‐messengers in Alzheimer's disease
It has long been assumed that widespread changes in postsynaptic neurotransmitter receptor function are not a feature of the… 
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