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amonafide L-malate

Known as: 5-amino-2-[2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione (2S)-2-ydroxybutanedioate, Butanedioic Acid, 2-hydroxy-, (2S)-, compd. with 5-amino-2-(2-(dimethylamino)ethyl)-1h-benz[de]isoquinoline-1,3(2h)-dione (1:1) 
The malate salt of amonafide, an imide derivative of naphthalic acid, with potential antineoplastic activity. Amonafide intercalates into DNA and… 
National Institutes of Health

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AS1413
amonafide

Papers overview

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2011
2011
A phase III, open-label, randomized comparison of AS1413 (amonafide L-malate) plus cytarabine with daunorubicin plus cytarabine in secondary acute myeloid leukemia (ACCEDE).
6520 Background: Secondary acute myeloid leukemia (sAML; after antecedent histologically documented myelodysplastic syndrome or… 
2008
2008
Amonafide L-malate is not a substrate for multidrug resistance proteins in secondary acute myeloid leukemia
Amonafide L-malate is not a substrate for multidrug resistance proteins in secondary acute myeloid leukemia 
2007
2007
Amonafide L-Malate Bypasses Multidrug Resistance Proteins in Secondary Acute Myeloid Leukemia.
Amonafide L-malate, a DNA intercalating agent and ATP-independent topoisomerase 2 inhibitor showed promising clinical activity in… 
2006
2006
Intramolecular energy transfer in a two-photon absorbing naphtahlimide-triphenylamine dyad
When a triphenylamine (TPA) is incorporated to a fluorephore of 2-Ethyl-6-(1-piperidinyl)-1H-benz[de]isoquinoline-1,3(2H dione… 
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