aminopyrimidine
National Institutes of Health
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Galactopyranosides with aryl-aminopyrimidine moieties at O3 inhibit the tumor and immunity-related galectin-3 with high…
A series of2-amino-4-aryl-6-ferrocenyl pyrimidines have been synthesized using cyclocondensation of 3-aryl-l-ferroccnyl-2-propen…
The lymphocyte-specific kinase (Lck), a member of the Src family of cytoplasmic tyrosine kinases, is expressed in T cells and…
Multireference ab initio dynamics simulations have become available as a tool for the investigation of photochemical processes…
Both solution and crystallographic studies suggest that the 4'-aminopyrimidine ring of the thiamin diphosphate coenzyme…
Background: AMN107, a selective and potent inhibitor of Bcr-Abl tyrosine kinase signaling, has demonstrated activity against…
A series of [4-[2(4-arylpiperazin-1-yl)alkyl]cyclohexyl]pyrimidin-2-ylamine s was prepared and found to have receptor binding…
ion from -NH2 in a ring-(NI) protonated species with k,'s of 310 sec-' and 150 sec-', respectively. The k, for either of these…