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ambasilide

Known as: 3-(4-aminobenzoyl)-7-benzyl-3,7-diazabicyclo(3.3.1)nonane 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

AminobenzoatesBridged Bicyclo Compounds, Heterocyclic

Narrower (1)

LU 47110

Papers overview

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Review
2008
Review
2008
Relationship among amiodarone, new class III antiarrhythmics, miscellaneous agents and acquired long QT syndrome.
Class III drugs prolong the QT interval by blocking mainly the delayed rectifier rapid potassium outward current (IKr), with… 
2007
2007
Effects of ambasilide in isolated perfused guinea pig heart
There has been increased interest in class III antiarrhythmic drugs for conversion of atrial fibrillation to sinus rhythm… 
2004
2004
Effects of the class III antiarrhythmic drug ambasilide on outward currents in human atrial myocytes
We have studied the inhibitory influence of the class III antiarrhythmic drug ambasilide (LU 47110) on the transient outward… 
2000
2000
Effects of ambasilide, quinidine, flecainide and verapamil on ultra-rapid delayed rectifier potassium currents in canine atrial myocytes.
2000
2000
Analysis of the electrophysiological effects of ambasilide, a new antiarrhythmic agent, in canine isolated ventricular muscle and purkinje fibers.
1999
1999
Ambasilide prolongs the action potential and blocks multiple potassium currents in human atrium.
Ambasilide (LU 47110) is a new class III antiarrhythmic drug with a unique profile of action in mammals; however, the effects on… 
1999
1999
The Influence of Specific and Nonspecific Potassium Current Blockade on the Defibrillation Energy Requirement of Biphasic Shock
Block of delayed rectifier potassium current (IK) is known to decrease defibrillation energy requirements (DERs). We tested the… 
Review
1999
Review
1999
Clinical Potential of Emerging Antiarrhythmic Agents
Analyses of randomised clinical trials have suggested that only in selective populations may antiarrhythmic drugs be effective in… 
1997
1997
Rate-independent effects of the new class III antiarrhythmic agent ambasilide on transmembrane action potentials in human ventricular endomyocardium.
The electrophysiologic effects of ambasilide, a new class III antiarrhythmic drug reported to be a nonselective blocker of both… 
1996
1996
Differential class III antiarrhythmic effects of ambasilide and dofetilide at different extracellular potassium and pacing frequencies.
We studied the effect of two new class II antiarrhythmics, ambasilide and dofetilide, on the action potential duration (APD) of… 
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