Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

alrestatin

Known as: 1,3-dioxo-1H-benz(de)isoquinoline-2(3H)- acetate, AY22,284 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
To realize the molecular design of new functional silver(I) clusters, a new synthetic approach has been proposed, by which the… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Angiotensin II (Ang II), a circulating hormone that can be synthesized locally in the vasculature, has been implicated in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1994
1994
Aldose reductase enfolds NADP+/NADPH via a complex loop mechanism, with cofactor exchange being the rate-limiting step for the… Expand
Is this relevant?
1991
1991
A variety of 2,4-dioxoquinazolineacetic acids (10, 11) were synthesized as hybrids of the known aldose reductase inhibitors… Expand
Is this relevant?
1990
1990
A broad group of structurally diverse aldose reductase inhibitors including flavonoids, carboxylic acids and hydantoins, have… Expand
Is this relevant?
1985
1985
Aldose reductase (alditol:NADP+ 1-oxidoreductase, EC 1.1.1.21) has been partially purified from human erythrocytes by DEAE… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
1982
1982
Human brain aldose reductase and hexonate dehydrogenase are inhibited by alrestatin (AY 22,284) and sorbinil (CP 45,634… Expand
Is this relevant?
Highly Cited
1981
Highly Cited
1981
The sorbitol pathway in human lenses is evaluated on the enzymic level. Adult lenses, normal and nondiabetic as well as diabetic… Expand
  • table I
  • figure 1
  • figure 2
  • figure 3
  • table II
Is this relevant?
1979
1979
Immediately after cataract extraction, lenses from diabetic and nondiabetic patients were collected, classified, and assayed or… Expand
Is this relevant?
1979
1979
Studies with the aldose reductase inhibitor alrestatin in animal models have suggested that the sorbitol pathway may be of… Expand
Is this relevant?