Skip to search formSkip to main contentSkip to account menu

alrestatin

Known as: 1,3-dioxo-1H-benz(de)isoquinoline-2(3H)- acetate, AY22,284 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Aldose reductase enfolds NADP+/NADPH via a complex loop mechanism, with cofactor exchange being the rate-limiting step for the… 
Highly Cited
1991
Highly Cited
1991
A variety of 2,4-dioxoquinazolineacetic acids (10, 11) were synthesized as hybrids of the known aldose reductase inhibitors… 
Highly Cited
1990
Highly Cited
1990
Highly Cited
1985
Highly Cited
1985
Highly Cited
1983
Highly Cited
1983
1982
1982
Abstract: Human brain aldose reductase and hexonate dehydrogenase are inhibited by alrestatin (AY 22,284) and sorbinil (CP 45,634… 
Highly Cited
1981
Highly Cited
1981
A single-blind, nonrandomized, placebo crossover clinical trial of an aldose reductase inhibitor, Alresta-tin (AY 22, 284) was… 
Highly Cited
1981
Highly Cited
1981
The sorbitol pathway in human lenses is evaluated on the enzymic level. Adult lenses, normal and nondiabetic as well as diabetic…