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alpha7 Nicotinic Acetylcholine Receptor

Known as: nAChR alpha7 Subunit, Nicotinic Acetylcholine Receptor alpha7, alpha7nAChR 
A member of the NICOTINIC ACETYLCHOLINE RECEPTOR subfamily of the LIGAND-GATED ION CHANNEL family. It consists entirely of pentameric ?7 subunits… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
T and B cells express most cholinergic system components—e.g., acetylcholine (ACh), choline acetyltransferase (ChAT… Expand
Review
2010
Review
2010
In recent years the etiopathology of a number of debilitating diseases such as type 2 diabetes, arthritis, atherosclerosis… Expand
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE The parasympathetic nervous system, through the vagus nerve, can down-regulate inflammation in vivo by decreasing the… Expand
Highly Cited
2009
Highly Cited
2009
The alpha7 nicotinic acetylcholine receptor (nAChR) is well established as the principal high-affinity alpha-bungarotoxin-binding… Expand
Highly Cited
2005
Highly Cited
2005
Herein we describe a novel series of compounds from which varenicline (1, 6,7,8,9-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The alpha7 neuronal nicotinic acetylcholine receptor subunit gene (CHRNA7) has been implicated as a candidate gene for… Expand
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Highly Cited
2002
Highly Cited
2002
Phenotypic modification of dorsal root ganglion (DRG) neurons represents an important mechanism underlying neuropathic pain… Expand
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Review
2002
Review
2002
Degradation of the essential amino acid tryptophan along the kynurenine pathway (KP) yields several neuroactive intermediates… Expand
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Highly Cited
2001
Highly Cited
2001
The tryptophan metabolite kynurenic acid (KYNA) has long been recognized as an NMDA receptor antagonist. Here, interactions… Expand
Highly Cited
2000
Highly Cited
2000
Alzheimer's disease pathology is characterized by the presence of neuritic plaques and the loss of cholinergic neurons in the… Expand