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alpha7 Nicotinic Acetylcholine Receptor

Known as: nAChR alpha7 Subunit, Nicotinic Acetylcholine Receptor alpha7, alpha7nAChR 
A member of the NICOTINIC ACETYLCHOLINE RECEPTOR subfamily of the LIGAND-GATED ION CHANNEL family. It consists entirely of pentameric ?7 subunits… 
National Institutes of Health

Related topics

Related topics

8 relations
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Narrower (3)

Receptor, alpha-Bungarotoxinchrna7 protein, zebrafishnAcRalpha-7E protein, Drosophila

Papers overview

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Highly Cited
2009
Highly Cited
2009
Proteomic analysis of an alpha7 nicotinic acetylcholine receptor interactome.
The alpha7 nicotinic acetylcholine receptor (nAChR) is well established as the principal high-affinity alpha-bungarotoxin-binding… 
Highly Cited
2007
Highly Cited
2007
An Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor Possessing Cognition-Enhancing Properties in Vivo
Augmentation of nicotinic α7 receptor function is considered to be a potential therapeutic strategy aimed at ameliorating… 
Highly Cited
2007
Highly Cited
2007
Nicotine alters lung branching morphogenesis through the alpha7 nicotinic acetylcholine receptor.
There is abundant epidemiological data linking prenatal environmental tobacco smoke with childhood asthma and wheezing, but the… 
Highly Cited
2007
Highly Cited
2007
Nanosecond-timescale conformational dynamics of the human alpha7 nicotinic acetylcholine receptor.
We explore the conformational dynamics of a homology model of the human alpha7 nicotinic acetylcholine receptor using molecular… 
Highly Cited
2002
Highly Cited
2002
Nicotine activates the extracellular signal‐regulated kinase 1/2 via the α7 nicotinic acetylcholine receptor and protein kinase A, in SH‐SY5Y cells and hippocampal neurones
Neuronal nicotinic acetylcholine receptors (nAChR) can modulate many cellular mechanisms, such as cell survival and memory… 
Highly Cited
2001
Highly Cited
2001
Membrane Lipid Rafts Are Necessary for the Maintenance of the α7 Nicotinic Acetylcholine Receptor in Somatic Spines of Ciliary Neurons
Calcium-permeable neurotransmitter receptors are concentrated into structurally and biochemically isolated cellular compartments… 
Review
1999
Review
1999
The alpha7 nicotinic acetylcholine receptor in neuronal plasticity.
A growing body of evidence indicates that neuronal nicotinic acetylcholine receptors (nAChRs), in addition to promoting fast… 
Highly Cited
1998
Highly Cited
1998
A decrease of reelin expression as a putative vulnerability factor in schizophrenia.
Postmortem prefrontal cortices (PFC) (Brodmann's areas 10 and 46), temporal cortices (Brodmann's area 22), hippocampi, caudate… 
Highly Cited
1998
Highly Cited
1998
Open-Channel Blockers at the Human α4β2 Neuronal Nicotinic Acetylcholine Receptor
To extend our knowledge of the pharmacological profile of human α4β2 neuronal nicotinic receptors, we investigated the action of… 
Highly Cited
1993
Highly Cited
1993
Characterization of Nicotinic Acetylcholine Receptors Expressed by Cells of the SH-SY5Y Human Neuroblastoma Clonal Line
Radioligand binding studies show that cells of the SH-SY5Y human neuroblastoma clonal line express a single class of neuronal… 
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