alpha7 Nicotinic Acetylcholine Receptor

Known as: nAChR alpha7 Subunit, Nicotinic Acetylcholine Receptor alpha7, alpha7nAChR 
A member of the NICOTINIC ACETYLCHOLINE RECEPTOR subfamily of the LIGAND-GATED ION CHANNEL family. It consists entirely of pentameric ?7 subunits… (More)
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Alpha7 nicotinic acetylcholine receptor (α7 nAChR) is an important part of the cholinergic nerve system in the brain. Moreover… (More)
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2009
2009
The alpha7 nicotinic acetylcholine receptor (nAChR) is well established as the principal high-affinity alpha-bungarotoxin-binding… (More)
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Review
2008
Review
2008
Alzheimer's disease (AD) is the leading cause of dementia affecting over 25 million people worldwide. Classical studies focused… (More)
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Highly Cited
2007
Highly Cited
2007
Augmentation of nicotinic alpha7 receptor function is considered to be a potential therapeutic strategy aimed at ameliorating… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The alpha7 neuronal nicotinic acetylcholine receptor subunit gene (CHRNA7) has been implicated as a candidate gene for… (More)
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Highly Cited
2001
Highly Cited
2001
Acetylcholine (ACh) is an important neurotransmitter in the mammalian brain; it is implicated in arousal, learning, and other… (More)
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Highly Cited
2001
Highly Cited
2001
The tryptophan metabolite kynurenic acid (KYNA) has long been recognized as an NMDA receptor antagonist. Here, interactions… (More)
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Highly Cited
2001
Highly Cited
2001
The transmission/disequilibrium test was used for fine mapping of the linkage of schizophrenia to the chromosome 15q13-14 region… (More)
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Highly Cited
2000
Highly Cited
2000
Alzheimer's disease pathology is characterized by the presence of neuritic plaques and the loss of cholinergic neurons in the… (More)
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Highly Cited
2000
Highly Cited
2000
We have recently reported evidence that a very high affinity interaction between the beta-amyloid peptide Abeta(1-42) and the… (More)
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