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alpha-Defensins

Known as: alpha Defensins, alpha-Defensins [Chemical/Ingredient] 
DEFENSINS found in azurophilic granules of neutrophils and in the secretory granules of intestinal PANETH CELLS.
National Institutes of Health

Related topics

Related topics

18 relations

Broader (2)

AlarminsAnti-Infective Agents

Narrower (8)

DEFA1A3 protein, humanRK-1 peptidecryptdin 4, mousedefensin NP-1
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Neutrophil defensins: their possible role in allergic asthma.
BACKGROUND Neutrophil defensins, originally identified as broad-spectrum antimicrobial peptides, have been implicated in the… 
2010
2010
HIV-1 exposed uninfected men who have sex with men have increased levels of salivary CC-chemokines associated with sexual behavior
Objectives:To determine whether soluble molecules with known anti-HIV-1 activity are increased in saliva of HIV-1 exposed… 
2009
2009
In vivo release of alpha-defensins in plasma, neutrophils and CD8 T-lymphocytes of patients with HIV infection.
alpha-Defensins are reported to be a soluble component of innate immunity actively participating in host defense against HIV. In… 
2007
2007
Leukotriene B4-mediated release of antimicrobial peptides against cytomegalovirus is BLT1 dependent.
Leukotriene B4 (LTB(4)) is a potent lipid mediator of inflammation that possesses antiviral activities. Here we provide evidence… 
2007
2007
Characterization of alpha-defensins plasma levels in Macaca fascicularis and correlations with virological parameters during SHIV89.6Pcy11 experimental infection.
Alpha-defensins have been shown to inhibit HIV-1 replication in vitro and may contribute to the overall control of viral… 
2005
2005
Inhibition of pathologic retinal neovascularization by alpha-defensins.
Proliferative retinopathies, such as those complicating prematurity and diabetes, are major causes of blindness. A prominent… 
2004
2004
&agr;-Defensins Released Into Stimulated CD8+ T-Cell Supernatants Are Likely Derived From Residual Granulocytes Within the Irradiated Allogeneic Peripheral Blood Mononuclear Cells Used as Feeders
Summary:We recently demonstrated the ability of human β-defensins to inhibit HIV-1 replication in vitro and demonstrated that… 
2004
2004
Elevated concentrations of alpha-defensins in gastric juice of patients with Helicobacter pylori infection.
OBJECTIVE Defensins (alpha- and beta-defensins) are endogenous antimicrobial peptides. Little is known about alpha-defensins… 
Highly Cited
2003
Highly Cited
2003
Defensin pattern in chronic gastritis: HBD-2 is differentially expressed with respect to Helicobacter pylori status
Background/Aims: Recent reports have suggested that Helicobacter pylori infection induces the mucosal antibiotic peptide human… 
2003
2003
Fc gamma RIIIb allele-sensitive release of alpha-defensins: anti-neutrophil cytoplasmic antibody-induced release of chemotaxins.
Antineutrophil cytoplasmic Abs (ANCA) can activate neutrophils in an FcgammaR-dependent manner, but the link between this ANCA… 
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