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alpha-Defensins

Known as: alpha Defensins, alpha-Defensins [Chemical/Ingredient] 
DEFENSINS found in azurophilic granules of neutrophils and in the secretory granules of intestinal PANETH CELLS.
National Institutes of Health

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2009
2009
Peripheral blood and tissue eosinophilia are a prominent feature in allergic diseases and during helminth infections. Eosinophil… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Psoriasis is characterized by epidermal infiltration of neutrophils that destroy invading microorganisms via a potent… Expand
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Highly Cited
2004
Highly Cited
2004
Background: Mutations in NOD2, a putative intracellular receptor for bacterial peptidoglycans, are associated with a subset of… Expand
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Highly Cited
2004
Highly Cited
2004
α-Defensins are peptides secreted by polymorphonuclear cells and provide antimicrobial protection mediated by disruption of the… Expand
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Highly Cited
2004
Highly Cited
2004
Although human CD56(+)CD3(-) natural killer (NK) cells participate in immune responses against microorganisms, their capacity to… Expand
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Highly Cited
2004
Highly Cited
2004
We tested the ability of 20 synthetic theta defensins to protect cells from infection by type 1 and type 2 herpes simplex viruses… Expand
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Highly Cited
2002
Highly Cited
2002
It has been known since 1986 that CD8 T lymphocytes from certain HIV-1-infected individuals who are immunologically stable… Expand
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Review
2001
Review
2001
Defensins and cathelicidins are the two major families of mammalian anti-microbial proteins. They contribute to host, innate… Expand
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Highly Cited
2000
Highly Cited
2000
We identified antibacterial components in human T and natural killer (NK) cells by using freshly isolated lymphocytes enriched… Expand
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Highly Cited
1996
Highly Cited
1996
We compared the expression of human alpha- and beta-defensins by various human tissues. mRNA for alpha-defensins HNP1-3, abundant… Expand
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