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alpha-2'-deoxythioguanosine

Known as: Alpha-Thioguanine Deoxyriboside, alpha-2'-Deoxy-6-thioguanosine, 6H-Purine-6-thione, 2-amino-9-(2-deoxy-alpha-D-erythro-pentofuranosyl)-1,9-dihydro- (9CI) 
A purine analog with potential antineoplastic activity. (NCI04)
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

DeoxyguanosineThionucleosides
NCIt Antineoplastic Agent Terminologyanalogs & derivatives

Narrower (1)

NSC-71851

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
LC-MS/MS coupled with stable isotope dilution method for the quantification of 6-thioguanine and S(6)-methylthioguanine in genomic DNA of human cancer cells treated with 6-thioguanine.
Thiopurines, including mercaptopurine (MP), 6-thioguanine ((S)G) and azathioprine, are widely used for the treatment of many… 
2008
2008
Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1…
The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a potent pulmonary carcinogen in rats… 
1982
1982
The stimulation of phosphofructokinase from human erythrocytes by fructose 2,6‐bisphosphate
Highly Cited
1979
Highly Cited
1979
Improved antitumor effects in 3'-branched homologues of 2'-deoxythioguanosine. Synthesis and evaluation of thioguanine nucleosides of 2,3-dideoxy-3-(hydroxymethyl)-D-erythro-pentofuranose.
The 3-(hydroxymethyl) branched homologue of 2-deoxyribofuranose was synthesized from the corresponding branched ribofuranose 2-O… 
1979
1979
Hypoxanthine uptake by human erythrocytes
1979
1979
Preparation of the diastereoisomers of beta-hydroxy-L-aspartate with pig heart aspartate aminotransferase.
1977
1977
Effects of stereochemical structures of tetrahydrobiopterin on tyrosine hydroxylase.
1969
1969
Purine Analogs as Potential Anticytomegalovirus Agents∗
Summary The activity of 25 purine analogs was determined against human cytomegalovirus in vitro. Nineteen compounds were… 
1967
1967
The utilization of alpha-2'-deoxythioguanosine by murine tumor cells.
The α- and β-anomers of 29-deoxythioguanosine were prepared with a radiocarbon label in the sugar moiety and a radiosulfur label… 
1966
1966
The GLC and TLC resolution of diastereoisomeric polyhydroxystearates and assignment of configurations
Trifluoroacetate (TFA) derivatives of methyl 12-hydroxystearate, methyl ricinoleate, five positional isomers of methylthreo… 
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