Semantic Scholar uses AI to extract papers important to this topic.
Free radicals such as reactive oxygen species (ROS) and reactive nitrogen species (RNS), which induce oxidative and nitrative… Expand Cumulative mtDNA damage occurs in aging animals, and mtDNA mutations are reported to accelerate aging in mice. We determined… Expand Oxygen radicals react with polyunsaturated fatty acid residues in phospholipids resulting in the production of a plethora of… Expand DNA damage is considered of paramount importance in aging. Among causes of this damage, free radical attack, particularly from… Expand Malondialdehyde is a naturally occurring product of lipid peroxidation and prostaglandin biosynthesis that is mutagenic and… Expand Damage to DNA seems to be involved in aging and the etiology of age-associated degenerative diseases. The purpose of this study… Expand Endogenous DNA adducts may contribute to the etiology of human genetic disease and cancer. One potential source of endogenous DNA… Expand A major theory of aging is that oxidative damage may accumulate in DNA and contribute to physiological changes associated with… Expand Deoxyribonucleic acid was covalently immobilized onto oxidized glassy carbon electrode surfaces that had been activated using 1… Expand The C-8 position of deoxyguanosine (dGuo) was hydroxylated by ascorbic acid in the presence of oxygen (O2) in 0.1 M phosphate… Expand