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almotriptan

Known as: 1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine, almotriptan [Chemical/Ingredient] 
A sulfonamide triptan with extracerebral, intracranial vasoconstrictor activity. Almotriptan selectively binds to and activates serotonin 5-HT 1B and… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (3)

AlmogranAlmotriptan malateAxert
Angina Pectoris, VariantCerebral Arterial Vasoconstriction [PE]Cluster HeadacheCoronary Artery Vasospasm

Broader (2)

Serotonin AgonistsTryptamines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Pharmacokinetics and Tolerability of Rizatriptan in Pediatric Migraineurs in a Randomized Study
Objective.— To evaluate the pharmacokinetic profile and tolerability of single doses of rizatriptan oral disintegrating tablets… 
Review
2011
Review
2011
Excellent Tolerability But Relatively Low Initial Clinical Efficacy of Telcagepant in Migraine
(Headache 2011;51:118‐123) 
2010
2010
Evolution of migraine-associated symptoms in menstrually related migraine following symptomatic treatment with almotriptan
In addition to headache, migraine is characterized by a series of symptoms that negatively affects the quality of life of… 
Review
2007
Review
2007
Factors affecting the relative importance of amine oxidases and monooxygenases in the in vivo metabolism of xenobiotic amines in humans
SummaryThe monooxygenases and the amine oxidases (AOs) are the major enzyme systems involved in vivo in the oxidative metabolism… 
2006
2006
Disposition and metabolism of almotriptan in rats, dogs and monkeys
Almotriptan is a new highly potent selective 5-HT1B/1D receptor agonist developed for the treatment of migraine, and the… 
Review
2005
Review
2005
Efficacy and Tolerability of Almotriptan in Controlled Clinical Trials
Seven triptans are now available for the acute treatment of migraine. While all of these agents have been shown to be safe and… 
Review
2004
Review
2004
Priorities for triptan treatment attributes and the implications for selecting an oral triptan for acute migraine: a study of US primary care physicians (the TRIPSTAR Project).
Review
2004
Review
2004
Clinical Profile and Practice Experience of Almotriptan
Patients expect their acute migraine treatment to have a rapid onset of action, achieve complete pain relief that is sustained… 
2004
2004
Pharmacokinetics and safety of oral almotriptan in healthy male volunteers
Almotriptan (LAS 31416) is a new, oral, specific 5‐hydroxytryptamine1B/1D receptor agonist for the treatment of migraine. The… 
Review
2001
Review
2001
Comparative aspects of triptans in treating migraine.
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