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alfimeprase
Known as:
3-203-Fibrolase (3-serine) (Agkistrodon contortrix contortrix recombinant)
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Metalloendopeptidases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Efficacy and safety of alfimeprase in patients with acute peripheral arterial occlusion (PAO).
S. Han
,
F. Weaver
,
A. Comerota
,
B. Perler
,
M. Joing
Journal of vascular surgery
2010
Corpus ID: 19073024
PURPOSE To investigate the safety and effectiveness of a novel thrombolytic, alfimeprase, in catheter-directed thrombolysis (CDT…
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2009
2009
Hemorrhagic profile of the fibrinolytic alfimeprase after ischemia and reperfusion
A. Lu
,
Y. Kurosawa
,
Kenneth L. Luskey
,
G. Pyne-Geithman
,
Danielle N. Caudell
,
J. Clark
Neurological research
2009
Corpus ID: 19368951
Abstract Objective: Recanalization therapies for ischemic stroke have been slow to change clinical practice because of perceived…
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2007
2007
Drug evaluation: alfimeprase, a plasminogen-independent thrombolytic.
A. Shah
,
L. Scher
IDrugs : the investigational drugs journal
2007
Corpus ID: 45328009
Alfimeprase is an analog of a fibrolase that disrupts formed thrombi through the hydrolysis of fibrin, rather than by activation…
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2006
2006
Phase II trial of alfimeprase, a novel-acting fibrin degradation agent, for occluded central venous access devices.
S. Moll
,
P. Kenyon
,
L. Bertoli
,
James De Maio
,
H. Homesley
,
S. Deitcher
Journal of clinical oncology : official journal…
2006
Corpus ID: 21010013
PURPOSE Alfimeprase is a recombinantly produced, genetically modified variant of the metalloproteinase, fibrolase. Alfimeprase…
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Review
2006
Review
2006
Alfimeprase: a novel recombinant direct-acting fibrinolytic
S. Deitcher
,
W. Funk
,
J. Buchanan
,
S. Liu
,
M. D. Levy
,
C. Toombs
Expert opinion on biological therapy
2006
Corpus ID: 30526851
Alfimeprase is a recombinant, direct-acting fibrinolytic zinc metalloprotease. Alfimeprase has direct proteolytic activity…
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2006
2006
Effect of thrombolysis on myocardial injury: recombinant tissue plasminogen activator vs. alfimeprase.
Ting-ting Hong
,
J. Huang
,
B. Lucchesi
American journal of physiology. Heart and…
2006
Corpus ID: 7850615
Plasmin-dependent thrombolytic agents are potentially prothrombotic and proinflammatory. Alfimeprase, a zinc-containing…
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Highly Cited
2005
Highly Cited
2005
Gateways to clinical trials.
M. Bayes
,
X. Rabasseda
,
J. Prous
Methods and findings in experimental and clinical…
2005
Corpus ID: 2206090
Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the…
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2005
2005
A phase I trial of alfimeprase for peripheral arterial thrombolysis.
K. Ouriel
,
J. Cynamon
,
+10 authors
S. Deitcher
Journal of vascular and interventional radiology…
2005
Corpus ID: 1098826
PURPOSE To evaluate the safety profile, pharmacokinetics, and thrombolytic activity of alfimeprase, a novel direct-acting…
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2004
2004
Contortrostatin, a dimeric disintegrin from contortrix contortrix, inhibits breast cancer progression
Qing Zhou
,
R. P. Sherwin
,
+4 authors
F. Markland
Breast Cancer Research and Treatment
2004
Corpus ID: 19497918
We report the results of a multidisciplinary study on the inhibitory effect of a snake venom disintegrin, contortrostatin, a 13.5…
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2001
2001
Disulfide structure of alfimeprase: A recombinant analog of fibrolase
G. Jones
,
M. Ronk
,
F. Mori
,
Z. Zhang
Protein science : a publication of the Protein…
2001
Corpus ID: 33911255
The disulfide structure of alfimeprase, a recombinant analog of fibrolase, was experimentally determined by a combination of…
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