Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

alfimeprase

Known as: 3-203-Fibrolase (3-serine) (Agkistrodon contortrix contortrix recombinant) 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
PURPOSE To investigate the safety and effectiveness of a novel thrombolytic, alfimeprase, in catheter-directed thrombolysis (CDT… Expand
2009
2009
Abstract Objective: Recanalization therapies for ischemic stroke have been slow to change clinical practice because of perceived… Expand
2007
2007
  • A. Shah, L. Scher
  • IDrugs : the investigational drugs journal
  • 2007
  • Corpus ID: 45328009
Alfimeprase is an analog of a fibrolase that disrupts formed thrombi through the hydrolysis of fibrin, rather than by activation… Expand
2006
2006
PURPOSE Alfimeprase is a recombinantly produced, genetically modified variant of the metalloproteinase, fibrolase. Alfimeprase… Expand
Review
2006
Review
2006
Alfimeprase is a recombinant, direct-acting fibrinolytic zinc metalloprotease. Alfimeprase has direct proteolytic activity… Expand
2006
2006
Plasmin-dependent thrombolytic agents are potentially prothrombotic and proinflammatory. Alfimeprase, a zinc-containing… Expand
  • table 1
  • figure 1
  • figure 2
  • table 2
  • table 3
Highly Cited
2005
Highly Cited
2005
Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the… Expand
2005
2005
PURPOSE To evaluate the safety profile, pharmacokinetics, and thrombolytic activity of alfimeprase, a novel direct-acting… Expand
2004
2004
We report the results of a multidisciplinary study on the inhibitory effect of a snake venom disintegrin, contortrostatin, a 13.5… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
2001
2001
The disulfide structure of alfimeprase, a recombinant analog of fibrolase, was experimentally determined by a combination of… Expand